- CEO
- Peter Ekolind
- Full Time Employees
- 9
- Sector
- Healthcare
- Industry
- Biotechnology
- Address
- Agavagen 52A Lidingö Sweden 181 55
- IPO Date
- May 25, 2015
- Business
- CombiGene AB (publ) develops gene therapies targeting severe neurological disorders with high unmet medical needs, including drug-resistant focal epilepsy and chronic pain conditions. The company focuses on adeno-associated virus-based gene therapy candidates such as CG01 for epilepsy seizure suppression via neuropeptide Y expression; the COZY program, comprising COZY01 (peptide-based) and COZY02 (gene therapy) targeting the PICK1 receptor for chronic pain; and earlier efforts like CGT2 for lipodystrophy in collaboration with Lipigon Pharmaceuticals AB. Operations center on preclinical research, proof-of-concept validation, and out-licensing to partners for clinical development and commercialization; CombiGene sources assets from academic collaborations including Lund University and University of Copenhagen, serving patient markets in neurology and biotechnology globally from headquarters in Stockholm, Sweden (visiting address: Skeppsbron 38, SE-111 30 Stockholm), founded in 1990. In October 2021, CombiGene entered an exclusive global licensing agreement with Spark Therapeutics (Roche subsidiary) for CG01, which Spark terminated in October 2023 amid strategic prioritization. In October 2024, the company sharpened focus on gene therapy by terminating the CG01 epilepsy program, implementing cost reductions projected to save SEK 57 million through Q2 2026, and extending liquidity; by January 2025, CombiGene discontinued all research activities and collaborations including the Zyneyro pain program agreement and divested its stake in CCRM Nordic AB, shifting toward strategic investments in cash-flow positive opportunities and partner evaluations for remaining assets. The company lists on Nasdaq First North Growth Market (ticker: COMBI.ST) with Certified Adviser FNCA Sweden AB.