GSK plc (GS7.DE) is a British multinational pharmaceutical and biotechnology company that discovers, develops, manufactures and markets human prescription and over-the-counter medicines, vaccines and other consumer healthcare-related products worldwide. Formed in 2000 through the merger of Glaxo Wellcome and SmithKline Beecham and headquartered in central London at 79 New Oxford Street, the company operates three primary business segments encompassing specialty medicines including HIV treatments such as Dovato and Cabenuva, oncology therapies like Zejula, immuno-inflammation and respiratory drugs such as Nucala and Trelegy Ellipta; vaccines featuring one of the industry's broadest portfolios with more than 20 marketed products targeting infectious diseases from birth through adulthood including Shingrix for shingles, Arexvy for RSV, meningococcal vaccines like Bexsero and Menquadfi, influenza vaccines, and established vaccines for rotavirus, hepatitis and polio; and general medicines prescribed in primary care settings including inhalers for asthma and COPD, antibiotics and other respiratory and HIV therapies. GSK maintains a global footprint with key operations in the U.S., Europe, U.K., Asia Pacific including China, Japan and India, Latin America and other emerging markets, serving healthcare providers, hospitals, pharmacies, governments and research institutions. Recent strategic developments include the January 2025 agreement to acquire IDRx Inc for up to $1.15 billion to bolster its gastrointestinal cancer portfolio with IDRX-42, a selective KIT tyrosine kinase inhibitor for gastrointestinal stromal tumors; a July 2025 collaboration with Hengrui Pharma involving a $500 million upfront payment for rights to up to 12 experimental therapies in respiratory, immunology and oncology outside greater China; a September 2025 pledge to invest $30 billion in U.S. R&D and manufacturing over five years including a $1.2 billion biologics facility in Pennsylvania for respiratory and cancer medicines; the July 2024 relocation of its headquarters from Brentford to New Oxford Street in central London; and the May 2024 divestiture of its remaining 4.2% stake in Haleon for $1.58 billion following the 2022 consumer healthcare demerger.