HUTCHMED (China) Limited (HCM.L) discovers, develops, and commercializes targeted therapies and immunotherapies for the treatment of cancer and immunological diseases. The company offers Fruquintinib (Elunate/Fruzaqla), a selective oral inhibitor of vascular endothelial growth factor receptors (VEGFR) 1, 2 and 3 approved for metastatic colorectal cancer; Savolitinib (Orpathys), a selective oral inhibitor of c-Met receptor tyrosine kinase for non-small cell lung cancer (NSCLC) and other solid tumors; Surufatinib (Sulanda), an oral inhibitor of VEGFR, FGFR and CSF-1R for neuroendocrine tumors; and Tazemetostat, an oral inhibitor of EZH2 for relapsed or refractory follicular lymphoma. Additional pipeline candidates include AMD3100 for stem cell mobilization in multiple myeloma and lymphoma; Sovleplenib for immune thrombocytopenia; and several early-stage assets such as HMPL-306, HMPL-760, HMPL-813, and HMPL-653 targeting various oncology and immunology indications. HUTCHMED operates primarily in oncology and immunology segments, serving patients and healthcare providers through partnerships with global pharmaceutical companies; its geographic footprint spans China, the United States, Europe, and other international markets. Founded in 2000 and headquartered in Hong Kong and Shanghai, China, the company maintains subsidiaries including Hutchison MediPharma Limited and collaborates with partners such as Takeda, Eli Lilly, and AstraZeneca for global development and commercialization.
In recent developments, HUTCHMED completed the acquisition of Inmagene Biopharmaceuticals in 2024, expanding its immunology portfolio with candidates like IMGN632; announced positive topline results from the Phase III SANET-ep trial for Surufatinib in neuroendocrine tumors in China during 2024; and secured FDA approval for Fruzaqla (fruquintinib) in the United States in November 2023, marking its first product launch outside China. The company also reported Phase II data for savolitinib in MET-driven NSCLC and initiated multiple global trials, including for tazemetostat following its 2024 acquisition from Epizyme. These advancements reflect HUTCHMED's strategic shift toward global expansion and late-stage pipeline maturation, bolstered by ongoing funding and partnerships.