Janus Henderson Global Select Fund Class R (JORRX) is an open-end mutual fund managed by Janus Henderson Investors that seeks long-term growth of capital by investing primarily in a portfolio of 40 to 70 domestic and foreign common stocks selected for their underestimated free-cash-flow growth potential; the fund employs a flexible all-cap approach across growth and value styles, with major holdings including Taiwan Semiconductor Manufacturing Co. Ltd., BAE Systems PLC, Microsoft Corp., Arthur J. Gallagher & Co., and NVIDIA Corp.; it maintains diversification across sectors such as technology (23.04%), financial services (17.88%), and consumer cyclical (15.54%), as well as regions including the United States (55.42%), United Kingdom (10.50%), and Eurozone (9.61%). The Class R shares, with a net expense ratio of 1.57% and a minimum initial investment of $2,500, were launched on July 6, 2009, and form part of a broader share class lineup offered by the fund, which has total net assets of approximately $2.86 billion. Managed by Julian McManus since January 2018 and co-managed by Christopher O'Malley since January 26, 2024, the fund is domiciled in the United States and available for sale therein. Janus Henderson Investors, the fund's investment manager, originated from the 2017 merger of Janus Capital Group (founded 1969 in Denver, Colorado) and Henderson Global Investors (roots in 1934 in London), and maintains global operations with headquarters in London, United Kingdom. In recent developments, Janus Henderson announced a strategic partnership with Guardian in April 2025, under which it assumed management of Guardian's $45 billion investment-grade public fixed income portfolio and received up to $400 million in seed capital for fixed income product innovation; the firm also launched the Janus Henderson Tabula US Transformational Growth Equity UCITS ETF (JTXX) in July 2025, targeting US companies in transformative trends like AI and deglobalization; additionally, in August 2024, it agreed to acquire a majority stake in Victory Park Capital to bolster private credit capabilities, expected to close in Q4 2024. Most notably, in October 2025, Janus Henderson confirmed receipt of a non-binding $7.2 billion acquisition proposal from Trian Fund Management and General Catalyst at $46 per share, prompting the board to form a special committee for review.