Roche Holding AG, founded in 1896 and headquartered in Basel, Switzerland, operates as a leading multinational healthcare company focused on pharmaceuticals and diagnostics; it develops and markets prescription medicines for oncology, immunology, infectious diseases, neuroscience, ophthalmology, haemophilia, inflammatory and respiratory diseases, and cardiovascular, renal and metabolic disorders; and offers a broad portfolio of in vitro diagnostic tests and instruments for diseases including cancer, diabetes, cardiovascular conditions, infectious diseases such as COVID-19, hepatitis and human papillomavirus, women's health, and point-of-care solutions like the recently FDA-cleared Liat Bordetella test for whooping cough; its diagnostics division encompasses professional diagnostics, molecular diagnostics, diabetes care, tissue diagnostics via Ventana, and digital health solutions for laboratories, healthcare providers and patients. The company conducts research and development, manufacturing and sales in more than 100 countries worldwide, serving physicians, hospitals, clinics, research institutions, pharmaceutical industries and consumers. Recent developments include a USD 50 billion investment over five years in US pharmaceuticals and diagnostics facilities for gene therapy, AI R&D and manufacturing expansions creating 12,000 jobs; entry into a definitive merger agreement in September 2025 to acquire 89bio and its phase 3 FGF21 analog pegozafermin for moderate to severe MASH; acquisitions of Carmot Therapeutics for USD 2.7 billion in 2024, Televant Holdings for USD 7.1 billion in 2023 and Good Therapeutics’ PD-1 programme; a USD 550 million expansion of its Indianapolis diagnostics manufacturing site by 2030 for continuous glucose monitoring; and multiple partnerships such as with Innovent Biologics for antibody-drug conjugates, Poseida Therapeutics for CAR-T therapy, and deals in China including with Regor Pharmaceuticals for CDK inhibitors.