- Business
- Samil Pharmaceutical Co., Ltd. manufactures and markets pharmaceutical products primarily in South Korea with international operations in Vietnam, Canada, and Japan. Founded in 1947 and headquartered in Seoul, the company offers a broad portfolio of prescription and over-the-counter medicines including hepatic and gastrointestinal drugs such as antiulcerants, gastroprokinetic agents, digestive enzymes, and laxatives under brands like Plybutine and Gliptide; antipyretic, analgesic, and anti-inflammatory agents under Brufen; nutritional supplements comprising vitamins, minerals, and immunosuppressants; circulatory drugs including vasodilators and antithrombotics; respiratory, antibiotic, neurological, metabolic, antihistamine, hormone, anti-tumor, urinary, and ophthalmic preparations such as artificial tears; skeletal muscle relaxants; gout and anti-parkinsonism agents; as well as OTC products, sanitary aids, dental preparations, disinfectants, and amino acids. Samil Pharmaceutical specializes in ophthalmology with partnerships including Allergan (AbbVie), Thea Pharma, and Samsung Bioepis for ranibizumab biosimilars, while expanding into contract development and manufacturing organization (CDMO) services focused on preservative-free eye drops and customized manufacturing. In September 2024, its Vietnam facility in Ho Chi Minh City's Saigon Hi-Tech Park received Good Manufacturing Practice certification from the Vietnam Drug Administration, enabling production of up to 300 million eye drop doses annually using advanced Blow-Fill-Seal and multi-filler equipment for global clients. The company entered strategic partnerships in June 2025 with SK Biopharmaceuticals and SK Networks' PhnyX Lab to develop Cheiron Write, an AI platform automating medical writing for drug development workflows, and holds exclusive South Korean rights to Biosplice Therapeutics' Lorecivivint, a Phase 3 knee osteoarthritis candidate with positive long-term trial data announced in December 2024.