- Business
- Hanall Biopharma Co., Ltd. (KRX: 009420.KS) is a global biopharmaceutical company that researches, develops, manufactures, and commercializes innovative specialty drugs, biologics, and generics targeting endocrine, circulatory, urologic, immunology, oncology, neurology, ophthalmology, and other therapeutic areas. Founded in 1973 and headquartered in Seoul, South Korea, with additional facilities in Daejeon and operations in the United States, Japan, and Indonesia, the company offers a portfolio of marketed products including Normix for acute enteritis and hyperammonemia; Biotop-D for intestinal regulation and constipation; Eligard for palliative treatment of prostate cancer; and Alphabon for hypocalcemia, tetany, and osteoporosis associated with vitamin D metabolism disorders; alongside antibiotics, amino acid formulations, and other prescription pharmaceuticals sold in South Korea and internationally. Its research and development pipeline features lead candidates such as batoclimab (HL161), a fully human anti-FcRn monoclonal antibody in Phase 3 and Phase 2 trials for myasthenia gravis, thyroid eye disease, chronic inflammatory demyelinating polyneuropathy, and Graves' disease; imeroprubart, an advanced FcRn inhibitor in development for cutaneous lupus erythematosus, Sjögren's disease, difficult-to-treat rheumatoid arthritis, and other autoimmune conditions; tanfanercept (HL036), a TNF-alpha inhibitor protein in Phase 3 studies for dry eye disease; and HL192, a Nurr-1 activator for Parkinson's disease.
In recent developments, Hanall Biopharma signed an exclusive global licensing agreement with Turn Biotechnologies in 2024 to develop mRNA-based epigenetic reprogramming therapies for age-related eye and ear conditions, valued at over $300 million for the initial product; announced the termination of its HL161 licensing agreement in 2025; received orphan drug designation for batoclimab in Japan; completed a Phase 1 study of HL192 (ATH-399A) with Daewoong Pharmaceutical and NurrOn Pharmaceuticals showing good tolerability; reported Q3 2024 revenue of 36.8 billion KRW; appointed Almira Chabi as Chief Medical Officer and Christopher W. Slavinsky as Chief Business Officer; and continued advancing multiple Phase 3 trials including VELOS-4 for tanfanercept.