- Business
- MedRx Co., Ltd. MedRx Co., Ltd engages primarily in the research, development, and formulation of pharmaceutical products utilizing advanced transdermal absorption technologies in Japan. The company develops innovative medicines based on its proprietary Ionic Liquid Transdermal System (ILTS) and Nano-sized Colloid Transdermal System (NCTS), which enhance drug solubility, absorbability, and efficacy while minimizing side effects and enabling administration for patients unable to take oral medications; its product pipeline includes MRX-4TZT in phase I clinical trials for spastic paralysis, MRX-9FLT in phase I for chronic, cancer, and severe pain, MRX-7MLL and MRX-6LDT in preclinical stages for Alzheimer’s disease and chronic pain, and MRX-5LBT that has completed clinical trials for postherpetic neuralgia, alongside efforts in painless transdermal delivery for vaccines, nucleic acid medicines, protein medicines, and microneedle array patch vaccines. MedRx Co., Ltd. also explores oral formulations using ionic liquid systems to improve absorbability of challenging active pharmaceutical ingredients (APIs) and seeks partnering opportunities for novel therapies. Founded in 2002 and headquartered in Higashikagawa, Japan, the company operates mainly in the pharmaceuticals sector with a focus on specialty transdermal and advanced drug delivery systems targeting nervous system disorders, pain management, and other unmet medical needs. Recent developments include a 2017 worldwide licensing agreement (excluding East Asia) with Cipla USA Inc. for MRX-4TZT, providing up to USD 30 million in milestone payments and tiered royalties, and a March 2025 private placement of 118,700 units of its 32nd Series Stock Acquisition Rights to raise funds for ongoing operations and development.