Cyfuse Biomedical K.K. (4892.T) develops, manufactures and sells regenerative medicine products and 3D bioprinting systems in Japan. The company offers Bio 3D Printers including regenova, a robotic system for fabricating 3D cellular structures from cell spheroids arranged in needle arrays; and S-PIKE, a next-generation printer for scaffold-free tissue engineering applicable to cartilage, bone, blood vessels, nerves and drug discovery models; alongside functional cellular devices as tools for pharmaceutical research and contract development of cell products. Founded in 2010 and headquartered in Minato-ku, Tokyo, with an additional office in Fukuoka, the firm targets healthcare providers, pharmaceutical companies and research institutions through its proprietary scaffold-free 3D printing platform. Recent developments include a 2025 joint announcement with PHC Corporation on innovative 3D cell product production technology for commercialization; business partnership with Marubeni Corporation for global expansion of S-PIKE; and sales alliance with Sysmex Corporation to market the printer; building on the 2023 strategic alliance with PHC to accelerate regenerative medicine pipelines.