- Business
- Jiangsu Hengrui Pharmaceuticals Co., Ltd. (600276.SS; 1276.HK) develops, manufactures and markets innovative pharmaceuticals targeting oncology, metabolic and cardiovascular diseases, immunology and respiratory conditions, neuroscience, anesthesia, anti-infection and autoimmune disorders; its core products encompass new molecular entity drugs such as Apalutamide, Nab-paclitaxel (Hengli) and Otilimab, alongside surgical medicines, endocrine therapies, cardiovascular drugs, contrast agents, proteolysis-targeting chimeras (PROTACs), peptides, monoclonal antibodies, bispecific antibodies (BsAbs), antibody-drug conjugates (ADCs) and radioligand therapies. Founded in 1970 and headquartered in Lianyungang, Jiangsu province, China, the company operates globally with R&D centers in China, the United States, Japan, Australia and Switzerland, subsidiaries in the US and Europe, and products available in over 40 countries including emerging markets; it maintains a pipeline of more than 100 innovative candidates across 400 clinical trials worldwide. In July 2025, Hengrui entered a landmark $500 million upfront collaboration with GSK to exclusively license HRS-9821 for chronic obstructive pulmonary disease and up to 11 additional preclinical candidates in respiratory, immunology, inflammation and oncology, with total potential value exceeding $12 billion; additional recent deals include a March 2025 agreement with Merck & Co. for oral lipoprotein(a) inhibitor HRS-5346 worth up to $1.97 billion and a May 2025 Hong Kong IPO raising $1.27 billion, alongside an exclusive license with Glenmark Pharmaceuticals for HER2 ADC Trastuzumab Rezetecan (SHR-A1811).