- Business
- 3-D Matrix, Ltd. (7777.T) develops, manufactures, and sells self-assembling peptide-based medical products for surgery, regenerative medicine, and drug delivery systems; its core offerings include PuraStat, a synthetic hemostatic gel in prefilled syringes for managing bleeding in gastrointestinal endoscopic procedures and reducing delayed bleeds post-submucosal dissection; PuraBond, a transparent hemostatic gel for vascular anastomoses and parenchymal bleeding in solid organs; and PuraSinus for sinus applications, along with associated accessories for endoscopic and laparoscopic use. Founded in 2004 as an MIT spinoff and headquartered in Tokyo, Japan, the company operates globally through subsidiaries and offices in the United States, United Kingdom, Australia, Singapore, the Netherlands, and France, targeting healthcare providers, surgeons, and research institutions across Americas, Europe, Middle East, and Asia. Recent developments include FDA 510(k) clearance for PuraStat-GI in gastrointestinal endoscopy and Japanese National Health Insurance listing in 2021; formation of 3-D Matrix Medical Technology Pty Ltd in Australia for direct sales in 2019; and a private placement of series 9th unsecured convertible bonds raising ¥1.103 billion from CVI Investments, Inc. in June 2025 to support growth.