American Century Investments One Choice 2045 Portfolio - I Class (AOOIX) is a target-date mutual fund offered by American Century Investments that seeks the highest total return consistent with its asset mix; as the approximate 2045 retirement target date approaches, the fund's allocation automatically shifts to a more conservative profile by reducing exposure to equities and increasing allocations to fixed income securities and cash equivalents. The portfolio invests primarily in a diversified mix of underlying American Century funds, including equity strategies such as American Century Large Cap Equity Fund G Class, American Century Growth Fund G Class, and American Century Focused Large Cap Value Fund G Class; fixed income components like American Century Diversified Bond Fund G Class and American Century Global Bond Fund G Class; and international offerings encompassing U.S. stocks (approximately 44.59%), non-U.S. stocks (21.09%), U.S. bonds (23.56%), non-U.S. bonds (8.43%), and cash (1.68%). Launched on August 31, 2004, and managed within the target-date 2045 category, AOOIX targets long-term investors planning retirement around 2045, with a minimum initial investment of $5 million for institutional clients and operations domiciled in the United States. American Century Investments, the fund's sponsor, was founded in 1958 and maintains headquarters in Kansas City, Missouri, with additional offices in New York, London, Hong Kong, Sydney, and other global locations. Recent developments include a decrease in the management fee schedule effective December 1, 2024, accompanied by a voluntary waiver of a portion of the fund's management fee through November 30, 2025, aimed at enhancing investor returns; additionally, American Century's Avantis Investors division entered a strategic alliance with CIBC Asset Management Inc. in November 2025 to launch eight new Avantis CIBC ETFs in Canada, reflecting broader expansion in ETF offerings.