- Business
- Bristol-Myers Squibb Company (NYSE: BMY; BMY.SW) is a global biopharmaceutical company that discovers, develops, and delivers innovative medicines for patients with serious diseases in oncology, hematology, immunology, cardiovascular, and neuroscience. The company, formed by the 1989 merger of Bristol-Myers (founded 1887) and Squibb (founded 1858), maintains headquarters in Princeton, New Jersey, with primary R&D sites in New Jersey, California, Massachusetts, Belgium, Japan, India, and the United Kingdom; it operates worldwide, generating 71% of 2024 revenues in the United States. Core products include Eliquis (apixaban; 28% of 2024 revenues) for stroke prevention in atrial fibrillation (co-marketed with Pfizer); Opdivo (nivolumab; 19%) for melanoma, lung cancer, and other solid tumors; Revlimid (lenalidomide; 12%) for multiple myeloma and myelodysplastic syndromes; Orencia (abatacept; 8%) for rheumatoid arthritis and other autoimmune diseases; Pomalyst/Imnovid (pomalidomide; 8%) for multiple myeloma and Kaposi sarcoma; Yervoy (ipilimumab; 5%) for cancer immunotherapy; Reblozyl (luspatercept; 4%) for anemia in beta thalassemia and myelodysplastic syndromes; CAR T therapies Abecma (idecabtagene vicleucel) and Breyanzi (lisocabtagene maraleucel) for relapsed/refractory multiple myeloma and lymphomas; Camzyos (mavacamten) for obstructive hypertrophic cardiomyopathy; and Cobenfy (xanomeline/trospium) for schizophrenia. Recent developments encompass acquisitions of Karuna Therapeutics ($14 billion; March 2024) adding KarXT/Cobenfy for neuroscience; RayzeBio ($4.1 billion; February 2024) for actinium-based radiopharmaceuticals in oncology; Mirati Therapeutics ($4.8 billion plus $1 billion milestones; January 2024) bolstering precision oncology; Turning Point Therapeutics ($4.1 billion; 2022) for repotrectinib; and Orbital Therapeutics (2025) enhancing in vivo CAR T for autoimmune diseases; a $286 million buyout of partner 2seventy bio (2025) securing full Abecma rights; new partnerships including Bain Capital (July 2025) for immunology therapies, BioNTech (June 2025) for bispecific BNT327 in solid tumors, Cellares ($380 million; April 2024) for CAR T manufacturing, and SystImmune ($250 million milestone; 2025) for iza-bren ADC in breast cancer; and FDA approval of Cobenfy (September 2024) as the first novel schizophrenia treatment in 70 years.