First Trust NYSE Arca Biotechnology Index Fund
FBT
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- First Trust NYSE Arca Biotechnology Index Fund (FBT) is an exchange-traded fund that seeks to replicate, to the extent possible, the performance of the NYSE Arca Biotechnology Index, comprising U.S.-listed biotechnology companies engaged in the research, development, production and marketing of products and services in the biotechnology industry, including recombinant DNA technologies, molecular biology, genetic engineering and related areas. The fund holds an equal-weighted portfolio of approximately 30 biotechnology stocks, with top holdings including Regeneron Pharmaceuticals Inc., Natera Inc., ACADIA Pharmaceuticals Inc., Incyte Corp. and Exact Sciences Corp.; it maintains a net expense ratio of 0.54%, total net assets of approximately $1.17 billion and daily pricing, primarily investing in U.S. equities (96.97% allocation) with minor exposure to non-U.S. stocks (2.91%) and cash. Launched on June 19, 2006, FBT is domiciled in the United States, managed by First Trust Advisors L.P. (headquartered in Wheaton, Illinois), and distributed by First Trust Portfolios L.P., with shares available for sale in the United States and Mexico. The fund operates within the health care sector, targeting investors seeking exposure to mid-cap blend biotechnology stocks classified under the Morningstar Health category. As of late 2025, no major recent partnerships, acquisitions, funding rounds, new product launches or strategic shifts specific to FBT have been reported, with the fund maintaining its core index-tracking strategy and periodic rebalancing to reflect index constituents.