Ionis Pharmaceuticals, Inc.

Ionis Pharmaceuticals, Inc.'s next confirmed earnings release is scheduled for November 4, 2026.

As of June 30, 2026, Ionis Pharmaceuticals, Inc. has 165.90M shares outstanding.

As of June 30, 2026, Ionis Pharmaceuticals, Inc. maintains a current ratio of 7.89, meaning it holds 7.9x the short-term assets needed to cover near-term liabilities. The debt-to-equity ratio is 366.93, indicating elevated leverage, while an interest coverage ratio of -6.88 demonstrates limited ability to service its debt obligations.

Over the twelve months ended June 30, 2026, Ionis Pharmaceuticals, Inc. posted a negative return on equity (ROE) of -105.50, meaning shareholder capital produced losses rather than profits. Return on assets (ROA) is negative at -18.90, reflecting losses generated across the asset base. The company generates approximately 580,163.11 in revenue per employee across its workforce of 1,318.75, a quick read on workforce productivity versus industry peers. Inventory turnover of 0.54 indicates how many times Ionis Pharmaceuticals, Inc. sells and replaces its inventory over a year, a key working capital efficiency ratio.

Over the twelve months ended June 30, 2026, Ionis Pharmaceuticals, Inc. recorded 2.78M in income tax expense. The company reported a pretax loss of -491.92M and -494.70M in bottom-line net income, so the effective tax rate carries little signal until profitability returns.

Over the twelve months ended June 30, 2026, Ionis Pharmaceuticals, Inc. generated 765.09M in revenue and converted that into -494.70M in net income, yielding earnings per share of -3.03. EBITDA reached -496.67M, while operating income came in at -520.30M.

As of June 30, 2026, Ionis Pharmaceuticals, Inc. holds 1.80B in cash and equivalents against 1.41B in total debt, resulting in a net debt position of 876.16M. Total book value stands at 384.90M, with working capital of 1.90B providing operational flexibility.

Ionis Pharmaceuticals, Inc. produced -434.53M in operating cash flow over the twelve months ended June 30, 2026. After subtracting -62.21M in capital expenditures, free cash flow totaled -496.74M - equivalent to -3.05 per share.

Over the twelve months ended June 30, 2026, Ionis Pharmaceuticals, Inc. posted a gross margin of 98.17, reflecting its pricing power and cost economics. The operating margin of -68.01 and net profit margin of -64.66 provide insight into operational efficiency.