Imugene Limited
Australian Securities ExchangeRecent
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- Imugene Limited Imugene Limited (ASX:IMU), a clinical-stage immuno-oncology company headquartered in Sydney, Australia, develops innovative immunotherapies that harness the immune system to treat and eradicate tumors in cancer patients; its primary platform technologies include an off-the-shelf allogeneic CAR T cell therapy azer-cel (azercabtagene zapreleucel) targeting CD19 for blood cancers such as relapsed/refractory diffuse large B-cell lymphoma, oncolytic virotherapy CF33 (VAXINIA) for solid tumors in combination with standard-of-care drugs and CAR T therapies, next-generation combination immunotherapy onCARlytics (CF33-CD19) to enhance CAR T responses in solid tumors by presenting CD19 antigen on cancer cells, and B-cell immunotherapies comprising cancer vaccines like HER-Vaxx against HER2 and PD1-Vaxx against PD-1. The company operates primarily in Australia with research facilities, partnerships, and clinical programs across the United States, focusing on both hematologic malignancies and solid tumors for patients with limited treatment options. Founded in 2013 and listed on the ASX since 1993, Imugene advances its pipeline through multiple Phase 1 and 1b clinical trials evaluating safety, efficacy, and combinations with emerging therapies. In recent developments, Imugene completed a $37.5 million capital raise in July 2025, including a $22.5 million placement and $15 million share purchase plan, to fund azer-cel trials in refractory lymphoma patients, and announced outstanding response rates from the Phase 1b azer-cel trial earlier that month; additionally, in April 2024, it entered a strategic manufacturing partnership with Kincell Bio, selling its North Carolina CGMP facility for up to $6 million USD while outsourcing azer-cel production and development to extend cash runway into 2026 and reduce staff by 50 percent.
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