- Business
- Invion Limited Invion Limited (ASX:IVX; OTC:IVIXF) is a clinical-stage Australian life sciences company focused on developing Photosoft technology, a next-generation photodynamic therapy (PDT) platform utilizing photosensitizing compounds, oxygen, and light to generate reactive oxygen species for selective cancer cell destruction and immune response activation; core products include the lead candidate INV043, a novel chlorin-based photosensitizer deliverable topically or intravenously for non-melanoma skin cancers, solid tumors such as ovarian, prostate, lung, glioblastoma, esophageal, triple-negative breast, pancreatic, anogenital, and colorectal cancers, as well as atherosclerosis and infectious diseases including periodontal conditions, viruses like Zika, Dengue, SARS-CoV-2, and antibiotic-resistant bacteria such as MRSA; the platform offers theragnostic capabilities for both treatment and imaging with minimal toxicity and synergy with immune checkpoint inhibitors. Founded in 2000 and headquartered in Melbourne, Australia, Invion holds exclusive perpetual licenses and distribution rights from RMW Cho Group for Photosoft in cancer indications across Australia, New Zealand, Asia Pacific (excluding China, Hong Kong, Macau, Taiwan, Japan), North America, and South Korea, with additional rights for infectious diseases in the US, Canada, and expanded Asian territories serving markets of over 3 billion people. Recent developments include the successful completion of a Phase II prostate cancer trial, ongoing Phase I/II non-melanoma skin cancer trial, planned Phase I/II anogenital cancer trial initiation in 2025, global IP extension to 2041 via new Australian patent grants for INV043, GMP-grade manufacturing, share consolidation to reduce overhangs, and capital-raising of up to A$6.8 million in June 2024 through institutional placements and share purchase agreements with Lind Partners; strategic pharma-funded collaborations with Hanlim Pharm for glioblastoma and esophageal cancer programs, Dr.inB for HPV-related indications, and research partnerships with Peter MacCallum Cancer Centre and Hudson Institute of Medical Research advance multiple oncology and infectious disease pipelines without IP dilution.