Janus Henderson Global Life Sciences Fund (JFNIX) is an open-end mutual fund that seeks long-term growth of capital by investing, under normal circumstances, at least 80% of its net assets in securities of companies with a life sciences orientation, including a fundamental policy to normally invest at least 25% of total assets in the life sciences sector; the portfolio maintains a balanced approach across subsectors such as biotechnology, health care services, medical devices, and pharmaceuticals, as well as across market capitalizations and geographies worldwide, with up to 20% in developing markets.
Managed primarily by Andy Acker since May 2007 and co-managed by Daniel Lyons since January 2023, the fund targets companies addressing unmet medical needs or enhancing health care system efficiency, employing fundamental analysis with bottom-up stock picking and an integrated risk management process using a security-level Value at Risk framework.
The fund, with total net assets of approximately $4.35 billion for the Class I shares, benchmarks against the MSCI World Health Care Index and operates within the Morningstar Health category, domiciled in the United States.
Janus Henderson Global Life Sciences Fund forms part of Janus Henderson Investors, a global asset manager formed from the 2017 merger of Janus Capital Group (founded 1969) and Henderson Group, headquartered in London, United Kingdom, with major offices in Denver, United States, and operations spanning 25 locations worldwide serving individual, intermediary, and institutional investors.
Recent developments include a commitment to a minimum level of sustainable investments effective November 2025 to meet client demand for SFDR-aligned exposure, alongside Janus Henderson's broader strategic initiatives such as the April 2025 multifaceted partnership with Guardian Life Insurance Company involving $45 billion in fixed income assets under management, up to $400 million in seed capital for product innovation, and equity warrants.