- Business
- Luye Pharma Group Ltd. (LYPHF) develops, manufactures, markets and sells innovative pharmaceutical products focused on central nervous system disorders, oncology, cardiovascular diseases, alimentary tract and metabolism conditions, orthopedics, neurology, gastroenterology, hepatology and gynecology; core offerings include extended-release injectable suspensions such as Erzofri (paliperidone palmitate), Rykindo (risperidone) and Ruiketuo (risperidone microspheres), transdermal drug delivery systems including Rivastigmine Twice Weekly Transdermal Patch and Rotigotine Transdermal Patch (Rotigotine Luye), liposomes and targeted therapies like Lipusu (paclitaxel liposome), Boyounuo (bevacizumab), Boyoubei/Boluojia (denosumab), Baituowei (goserelin microspheres), biopharmaceuticals such as Zepzelca (lurbinectedin), Ruoxinlin (toludesvenlafaxine hydrochloride sustained-release tablets), Jinyouping (rotigotine microspheres for injection), Mimeixin (oxycodone hydrochloride and naloxone hydrochloride sustained-release tablets), Boyouping (dulaglutide injection) and Boyoujing (aflibercept intravitreous injection), alongside Seroquel/Seroquel XR, Xuezhikang and other drugs leveraging long-acting, sustained-release, liposome, transdermal and novel compound technologies through subsidiaries like Shandong Boan Biotechnology. Founded in 1994 and headquartered in Yantai, Shandong Province, China, the company operates R&D centers in China, the U.S. and Europe, eight GMP-compliant manufacturing sites including seven in China and one in Germany, and commercializes over 30 products across more than 80 countries and regions encompassing China, the U.S., Europe, Japan and emerging markets. Recent developments encompass multiple new drug approvals from 2021-2025 including 15 innovative therapies in the U.S., Europe, Japan and China such as Rivastigmine Twice Weekly Transdermal Patch in Japan (2025), Erzofri in the U.S. (2024) and six China approvals in 2024; FDA clearance of IND for next-generation CNS candidate LY03017 targeting Alzheimer's disease psychosis, Parkinson's disease psychosis and schizophrenia negative symptoms (November 2025); upgrade of international innovation strategy to Version 3.0 driven by in-house development and business development operations with new product sales up 32% in 2025 half-year results; strategic investment in Shenzhen Luye to advance oncology R&D, market access and collaborations (July 2024); and ongoing Phase 3 enrollment for Ruoxinlin and Phase 1 initiation for LY03021.