OPKO Health, Inc.

OPKO Health, Inc.

OPK.TA
OPKO Health, Inc.IL flagTel Aviv Stock Exchange
458.50
ILA
-3.30
- -
3.46BMarket Cap
OPKO Health, Inc.
OPK.TA
(Tel Aviv Stock Exchange)

Recent

price

458.50

P/E

ratio

- -

div

yld

- -

ROIC.AI

2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
TTM
FRC
0.11
0.1
0.16
0.27
0.22
0.98
2.23
1.73
1.75
1.51
2.24
2.74
1.4
1.15
1.03
0.81
0.75
Revenue per Share
-0.08
-0.01
-0.11
-0.32
-0.41
-0.06
-0.1
-0.55
-0.27
-0.53
0.05
-0.05
-0.46
-0.25
-0.08
-0.3
-0.28
Basic EPS, GAAP
-0.07
-0.07
-0.09
-0.16
-0.22
0.32
0.05
-0.16
-0.19
-0.29
0.06
0.06
-0.13
-0.04
-0.26
-0.24
-0.21
Free Cash Flow per Basic Share
- -
0.02
- -
0.01
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Dividend per Share
-1.39
-1.27
-1.3
-1.41
-1.6
-1.4
-1.44
-1.87
-2.1
-2.53
-2.3
-2.32
-2.52
-2.67
-2.97
-3.04
-3.03
Book Value per Share
0.03
0.16
0.01
-0.62
-0.58
-0.39
-0.04
-0.37
-0.28
-0.3
-0.12
0.39
-0.07
-0.19
0.04
0.1
0.04
Tangible Book Value per Share
255
281
296
355
419
500
502
559
567
595
641
648
719
752
694
751
771
Basic Weighted Avg Shares
28
28
47
97
91
492
1,117
966
990
902
1,435
1,775
1,004
863
713
607
581
Sales/Revenue/Turnover
-39.08
- -
- -
- -
- -
- -
-7.12
-27.61
- -
- -
- -
- -
- -
- -
- -
- -
-34.9
Operating Margin (%)
2
4
10
15
15
42
97
102
97
94
85
79
109
105
98
92
90
Depreciation Expense
-19
-1
-29
-114
-172
-30
-48
-305
-153
-315
31
-30
-328
-189
-53
-226
-213
Net Income, GAAP
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
36.19
- -
- -
- -
- -
- -
47.78
Effective Tax Rate (%)
-66.42
-4.59
-61.75
-118.52
-188.39
-6.11
-4.33
-31.6
-15.45
-34.92
2.13
-1.7
-32.7
-21.87
-7.46
-37.19
-36.64
Profit Margin (%)
26
81
26
151
60
202
220
37
29
75
148
493
181
109
469
435
387
Working Capital
- -
- -
5
215
134
133
90
143
173
292
258
226
255
283
475
374
375
LT Debt
23
185
203
873
836
1,980
2,092
1,844
1,791
1,615
1,672
1,685
1,562
1,389
1,365
1,268
1,205
Total Equity
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
-3.76
- -
- -
- -
- -
- -
-3.09
Return on Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Common Equity (%)

Capital Structure

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
ST Debt
24
23
22
LT Borrowings
331
334
336
LT Finance Leases
40
40
39
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
769
759
755
Market Capitalization
105,941
94,969
87,813

Working Capital

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
Total Current Assets
627
582
535
Cash, Cash Equivalents & STI
415
369
342
Accounts Receivable, Net
95
90
80
Inventories
65
66
64
Total Current Liabilities
169
147
148
Payables & Accruals
101
84
85
ST Debt
24
23
22
Deferred Revenue
- -
- -
- -

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
-4.18%
-5.28%
-7.14%
Free Cash Flow
-44.33%
25.29%
-2.7%
Net Income, GAAP
153.91%
200.13%
324.02%
Sales/Revenue/Turnover
10.03%
-13.22%
-14.9%
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
174
182
174
184
713
2025
150
157
152
148
607
2026
124
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-0.12
-0.01
0.04
0.02
-0.08
2025
-0.1
-0.19
- -
-0.04
-0.3
2026
-0.07
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -
Business
OPKO Health, Inc. (Nasdaq: OPK; TASE: OPK) is a multinational biopharmaceutical and diagnostics company that discovers, develops, manufactures, and commercializes proprietary pharmaceuticals, diagnostic tests, and laboratory services for serious diseases including chronic kidney disease, growth hormone deficiency, prostate cancer, oncology, and infectious diseases; core products and services include the Rayaldee extended-release calcifediol capsule for secondary hyperparathyroidism; the 4Kscore Test for assessing aggressive prostate cancer risk; VARUBI oral suspension for chemotherapy-induced nausea and vomiting; the BioReference Laboratories network offering clinical reference testing in genetics, oncology, women's health, and urology across the United States with core operations in New York and New Jersey; point-of-care tests, molecular diagnostics, and advanced imaging technologies; biologic therapies such as monoclonal antibodies; and multispecific antibody programs targeting cancers, immunology, metabolic diseases, influenza, and COVID-19 through subsidiaries and partnerships. Founded in 1991 and headquartered in Miami, Florida, the company operates globally with established markets in North America, Europe, and beyond, serving physicians, patients, hospitals, and pharmaceutical partners through its diversified segments of pharmaceuticals and diagnostics. Recent developments include the March 2025 agreement and September 2025 completion of Labcorp's acquisition of select BioReference Health oncology and clinical testing assets for up to $225 million to streamline operations and focus on core testing and the 4Kscore franchise; a July 2024-initiated and April 2025-expanded $200 million common stock repurchase program with $41 million repurchased by April; $51 million in additional BARDA funding awarded in early 2025 for ModeX Therapeutics' COVID-19 multispecific antibodies and influenza programs, bringing total awards to $110 million; enrollment in the MDX2001 Phase 1 trial for tetraspecific antibodies in solid tumor cancers; and a November 2025 collaboration with Regeneron involving a $7 million upfront payment, over $200 million per-molecule milestones, low double-digit royalties, and potential value exceeding $1 billion for multispecific therapeutics in immunology, oncology, and metabolic diseases.