- Business
- PCI Biotech Holding ASA PCI Biotech Holding ASA, a biopharmaceutical company listed on the Oslo Stock Exchange, develops and commercializes technologies and novel therapies based on its proprietary photochemical platform, including photochemical lysis (PCL) for enhancing viral vector manufacturing yield and purity in gene therapy bioprocessing, and photochemical internalization (PCI) for light-triggered intracellular release of therapeutics in areas such as immunotherapy, dermatology, and oncology. The platform utilizes the small molecule photosensitizer fimaporfin (Amphinex) combined with a light source to enable targeted drug delivery, supporting applications like fimaCHEM for enhancing chemotherapeutic drugs in localized cancer treatment, fimaVACC for inducing T-cell responses in therapeutic cancer vaccination, and fimaNAc for nucleic acid therapeutics in dermatological diseases; the company operates primarily in research and development with a focus on oncology and gene therapy markets in Europe. Founded in 2007 and headquartered in Oslo, Norway, at Oslo Cancer Cluster Innovation Park, PCI Biotech Holding ASA targets pharmaceutical and biotech partners globally through its partnering model. In August 2025, the company discontinued development of its PCL technology for viral vector bioprocessing and initiated an evaluation of future operations, as announced in its half-year 2025 interim report and subsequent updates in September and October 2025; recent activities include recruitment of key scientific personnel such as a new Chief Scientific Officer in early 2025 with associated employee share option schemes, alongside routine financial reporting and annual general meetings in 2025.