AXS 2X PFE Bear Daily ETF (PFES) is an actively managed exchange-traded fund that seeks daily investment results, before fees and expenses, corresponding to two times the inverse (-200%) of the daily performance of Pfizer Inc. (PFE) common stock. Launched on July 14, 2022, by Investment Managers Series Trust II and managed by AXS Investments LLC, the ETF employs derivative instruments such as swaps to achieve its leveraged short exposure strategy targeting the U.S. pharmaceuticals sector. Headquartered in Port Chester, New York, AXS Investments, founded in 2019, specializes in alternative investment ETFs providing growth, income, and diversification opportunities.
The fund's primary product offering centers on leveraged inverse daily exposure to PFE shares through a portfolio constructed via derivatives, focusing on healthcare, pharmaceuticals, biotechnology, and life sciences stocks without direct equity holdings. It targets sophisticated investors seeking short-term tactical trading opportunities in the single-stock inverse equity niche, with an expense ratio of approximately 1.15% and operations limited to U.S. markets.
In a significant operational change, Investment Managers Series Trust II liquidated the AXS 2X PFE Bear Daily ETF on June 26, 2023, distributing cash proceeds to remaining shareholders following anticipated closure announcements earlier that month. This closure occurred amid broader ETF market dynamics, including challenges for single-stock leveraged products launched during the 2020-2022 period, with PFES realizing substantial gains prior to liquidation driven by PFE's share decline. No subsequent relaunches, partnerships, or strategic shifts related to PFES have been reported as of late 2025.