Scancell Holdings plc (LSE:SCLP) is a clinical-stage biopharmaceutical company that develops novel immunotherapies targeting cancer through proprietary platforms including ImmunoBody and Moditope for vaccines; GlyMab and AvidiMab for monoclonal antibodies. ImmunoBody vaccines, such as SCIB1, iSCIB1+, SCIB2, SC129 and SC134, stimulate CD4 and CD8 T-cell responses against tumor-specific peptides to induce potent, durable anti-tumor immunity in solid tumors including metastatic melanoma; Moditope vaccines, such as Modi-1 and Modi-2, target citrullinated and homocitrullinated peptides to harness T-cell responses against a broad range of solid tumors; GlyMab antibodies, including SC2811 and SC27, enhance antibody-dependent cellular cytotoxicity by modifying glycan structures on monoclonal antibodies; AvidiMab enhances antibody potency through molecular modifications. The company, founded in 1996 and headquartered at Bellhouse Building, Oxford Science Park, Oxford, England, operates primarily in the United Kingdom with a pipeline focused on unmet needs in oncology across multiple solid tumor indications. Recent developments include a partnership with the NHS Cancer Vaccine Launchpad for fast-tracked access to SCOPE trials in melanoma patients; a strategic alliance with PharmaJet for the Stratis needle-free injectable device in iSCIB1+ studies; a second commercial license agreement with Genmab yielding $6 million upfront and potential milestones of $630 million plus royalties, validating the GlyMab platform; incorporation of GlyMab Therapeutics Limited as a wholly-owned subsidiary in June 2025; and accelerated plans for randomized registration studies of iSCIB1+ starting in 2026 following Phase 2 data.