As of June 30, 2026, Vertex Pharmaceuticals Incorporated carries a market capitalization of 110.31B, placing it among publicly traded companies globally. Its enterprise value stands at 105.17B, reflecting the total theoretical takeover cost after accounting for cash holdings and debt obligations.
| Market Cap | 110.31B |
| Enterprise Value | 105.17B |
Vertex Pharmaceuticals Incorporated's next confirmed earnings release is scheduled for November 2, 2026.
| Earnings Date | 11/2/2026 |
As of June 30, 2026, Vertex Pharmaceuticals Incorporated has 253.35M shares outstanding.
| Shares Outstanding | 253.35M |
As of June 30, 2026, Vertex Pharmaceuticals Incorporated trades at a trailing price-to-earnings ratio of 28.72. The price-to-sales ratio is 10.05, and the price-to-book ratio stands at 6.22.
| PE Ratio | 28.72 |
| PS Ratio | 10.05 |
| PB Ratio | 6.22 |
| P/TBV Ratio | 6.72 |
| P/FCF Ratio | 33.58 |
| P/OCF Ratio | 29.47 |
As of June 30, 2026, Vertex Pharmaceuticals Incorporated trades at an EV/EBITDA multiple of 24.03 - the valuation measure that neutralizes differences in capital structure, tax rates, and depreciation policy, making it the standard yardstick for comparing companies across an industry. The EV/Sales ratio of 9.55 reflects the premium investors pay for the company's revenue stream, a useful check when earnings are depressed or negative. Its EV/EBIT multiple of 25.15 values the business against core operating earnings after depreciation, a stricter test than EV/EBITDA for capital-intensive businesses. Vertex Pharmaceuticals Incorporated trades at an EV/FCF ratio of 31.60, comparing the total takeover cost of the business to the cash it actually generates for all capital providers. These enterprise value multiples are built on an enterprise value of 105.17B versus a market cap of 110.31B, with the gap driven by net debt and cash on the balance sheet.
| EV / Sales | 9.55 |
| EV / EBITDA | 24.03 |
| EV / EBIT | 25.15 |
| EV / FCF | 31.60 |
As of June 30, 2026, Vertex Pharmaceuticals Incorporated maintains a current ratio of 3.19, meaning it holds 3.2x the short-term assets needed to cover near-term liabilities. The debt-to-equity ratio is 9.77, indicating elevated leverage, while an interest coverage ratio of 757.45 demonstrates strong ability to service its debt obligations.
| Current Ratio | 3.19 |
| Quick Ratio | 2.54 |
| Debt / Equity | 9.77 |
| Debt / EBITDA | 0.40 |
| Interest Coverage | 757.45 |
Over the twelve months ended June 30, 2026, Vertex Pharmaceuticals Incorporated posted a return on equity (ROE) of 23.54, showing how much profit the company earns on every dollar of shareholder capital. Return on invested capital (ROIC) comes in at 19.50 - the clearest signal of whether the business earns more on its capital than that capital costs, and the core measure of a durable competitive advantage. Return on assets (ROA) stands at 17.12, measuring how efficiently the asset base is converted into earnings. Return on capital employed (ROCE) is 21.55, useful for judging operating efficiency across full business cycles. The company generates approximately 1.74M in revenue per employee across its workforce of 6,325.00, a quick read on workforce productivity versus industry peers. Inventory turnover of 1.08 indicates how many times Vertex Pharmaceuticals Incorporated sells and replaces its inventory over a year, a key working capital efficiency ratio.
| Return on Equity (ROE) | 23.54 |
| Return on Assets (ROA) | 17.12 |
| Return on Invested Capital (ROIC) | 19.50 |
| Return on Capital Employed (ROCE) | 21.55 |
| Revenue Per Employee | 1.74M |
| Employee Count | 6,325.00 |
| Inventory Turnover | 1.08 |
Over the twelve months ended June 30, 2026, Vertex Pharmaceuticals Incorporated recorded 760.90M in income tax expense. That works out to an effective tax rate of 16.48, which can sit above or below the statutory corporate tax rate depending on foreign earnings mix, tax credits, and one-off items. Taxes are levied on pretax income of 4.62B, leaving 3.86B in net income after tax - the gap is what shifts in the tax rate do to reported earnings and EPS.
| Income Tax | 760.90M |
| Effective Tax Rate | 16.48 |
As of the close on October 22, 2026, Vertex Pharmaceuticals Incorporated's stock has gained approximately 29.58% over the past 52 weeks. The 50-day moving average sits at 457.44, while the 200-day moving average is 413.38.
| 52-Week Price Change | 29.58% |
| 50-Day Moving Average | 457.44 |
| 200-Day Moving Average | 413.38 |
Over the twelve months ended June 30, 2026, Vertex Pharmaceuticals Incorporated generated 11.02B in revenue and converted that into 3.86B in net income, yielding earnings per share of 15.04. EBITDA reached 4.38B, while operating income came in at 4.18B.
| Revenue | 11.02B |
| Gross Profit | 9.47B |
| Operating Income | 4.18B |
| Pretax Income | 4.62B |
| Net Income | 3.86B |
| EBITDA | 4.38B |
| EBIT | 4.18B |
| Earnings Per Share (EPS) | 15.04 |
As of June 30, 2026, Vertex Pharmaceuticals Incorporated holds 6.87B in cash and equivalents against 1.73B in total debt, resulting in a net debt position of -5.38B. Total book value stands at 17.72B, with working capital of 7.53B providing operational flexibility.
| Cash & Cash Equivalents | 6.87B |
| Total Debt | 1.73B |
| Net Debt | -5.38B |
| Equity (Book Value) | 17.72B |
| Book Value Per Share | 69.96 |
| Working Capital | 7.53B |
Vertex Pharmaceuticals Incorporated produced 3.76B in operating cash flow over the twelve months ended June 30, 2026. After subtracting -434.85M in capital expenditures, free cash flow totaled 3.32B - equivalent to 13.06 per share.
| Operating Cash Flow | 3.76B |
| Capital Expenditures | -434.85M |
| Free Cash Flow | 3.32B |
| FCF Per Share | 13.06 |
Over the twelve months ended June 30, 2026, Vertex Pharmaceuticals Incorporated posted a gross margin of 86.00, reflecting its pricing power and cost economics. The operating margin of 37.95 and net profit margin of 35.00 provide insight into operational efficiency.
| Gross Margin | 86.00 |
| Operating Margin | 37.95 |
| Pretax Margin | 41.90 |
| Profit Margin | 35.00 |
| EBITDA Margin | 39.72 |
These figures cover the twelve months ended June 30, 2026. Free cash flow yield stands at 2.98, showing how much cash the business generates relative to its market value - dividends covered by free cash flow are generally more durable than those funded by debt. Total shareholder yield reaches 1.74, combining dividends paid with share buybacks and debt reduction for a fuller picture of capital returned to Vertex Pharmaceuticals Incorporated shareholders.
| Shareholder Yield | 1.74 |
| FCF Yield | 2.98 |
Vertex Pharmaceuticals Incorporated's most recent stock split took place on August 24, 2000 with a 1:2 split ratio.
| Last Split Date | 8/24/2000 |
| Split Ratio | 1:2 |
As of June 30, 2026, Vertex Pharmaceuticals Incorporated has an Altman Z-Score of 12.88, well above the 3.0 threshold that indicates strong financial health and minimal bankruptcy risk.
| Altman Z-Score | 12.88 |