- Business
- Vaxil Bio Ltd. (TSXV: VXL) is a Canada-based biotechnology company focused on a novel drug discovery and development platform based on signal peptides (SPs) to target cancer and infectious diseases. The company develops ImMucin, a MUC1 SP-derived vaccine that has completed a Phase I/II clinical trial for multiple myeloma treatment and received orphan drug status from the FDA and EMA; monoclonal antibody candidates including SPmAb2 and SPmAb6 for oncology and infectious diseases; MTbuVax, a tuberculosis vaccine/treatment candidate; and a SP-based COVID-19 vaccine candidate, along with P-Esbp-DOX, a drug delivery polymer targeting E-selectin licensed from BGN Technologies. Founded in 2006 and headquartered in Toronto, Ontario, with operations linked to Rehovot, Israel, Vaxil Bio Ltd. primarily serves the immuno-oncology and infectious disease markets through its proprietary VaxHit bioinformatic platform that identifies universal neoantigens. In August 2024, the company entered a definitive amalgamation agreement with Green Data Centers for a reverse takeover and change of business to data center development, which was subsequently terminated, with Green Data Centers required to repay a related loan by July 2025; it also completed a 1-for-50 reverse stock split effective May 15, 2025, and announced a non-brokered private placement update in November 2025 to explore capital sources for ongoing SP platform advancements.