- Business
- CureVac N.V. CureVac N.V. (Ticker: 5CV.F), a clinical-stage biopharmaceutical company headquartered in Tübingen, Germany, and founded in 2000, develops transformative medicines based on proprietary messenger RNA (mRNA) technology. The company focuses on prophylactic vaccines for infectious diseases including SARS-CoV-2 variants, influenza, and urinary tract infections caused by uropathogenic E. coli; oncology treatments such as off-the-shelf and personalized cancer precision immunotherapies targeting squamous non-small cell lung cancer and glioblastoma; and molecular therapies that enable cells to produce therapeutic proteins. CureVac optimizes mRNA constructs with customized 5’ and 3’ untranslated regions and open reading frames, supported by carrier molecules like lipid nanoparticles developed in partnership with Acuitas Therapeutics and Arcturus Therapeutics; it also offers the RNA Printer, an automated system for mRNA vaccine and therapeutic manufacturing. Operations span Germany, the Netherlands, Belgium, Switzerland, and the United States, with collaborations including GlaxoSmithKline (GSK) GSK plc for influenza and COVID-19 vaccines—restructured in 2024 into a licensing agreement providing CureVac €400 million upfront and up to €1.05 billion in milestones plus royalties—and ongoing patent litigation against Pfizer Pfizer Inc./BioNTech BioNTech SE. In June 2025, BioNTech announced a definitive all-stock acquisition of CureVac valued at approximately USD 1.25 billion, with German regulatory clearance granted by November 2025 ahead of an extraordinary general meeting.