Aptose Biosciences Inc.

Aptose Biosciences Inc.

APTO
Aptose Biosciences Inc.US flagNASDAQ Capital Market
1.71
USD
+1.71
- -
4.36MMarket Cap
2012 Y
2013 Y
2014 Y
2015 Y
2016 Y
2017 Y
2018 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
TTM
Revenue per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Basic EPS, GAAP
-1,193.69
-690.1
-839.06
-442.64
-502.88
-234.81
-389.05
-235.74
-303.74
-330.12
-203.98
-227.43
-36.38
-19.37
Free Cash Flow per Basic Share
-856.59
-631.07
-680.44
-383.6
-437.65
-206.44
-317.19
-194.32
-186.79
-219.81
-157.76
-198.17
-51.48
-24.53
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-6,301.66
-3,154.37
192.89
-324.26
-603.63
-299.43
-196.3
570.35
397.95
75.16
-130.76
-314.14
-119.55
-78.77
Tangible Book Value per Share
-524.66
-96.85
2,261.16
514.17
257.92
205.75
189.77
842.64
653.89
374.99
184.07
-12.88
-6.5
-6.71
Basic Weighted Avg Shares
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
1
1
Sales/Revenue/Turnover
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Operating Margin (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Depreciation Expense
- -
- -
- -
- -
- -
- -
- -
1
1
1
1
- -
- -
- -
Net Income, GAAP
-4
-5
-10
-12
-14
-12
-29
-26
-55
-65
-42
-51
-25
-21
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Profit Margin (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Working Capital
-2
-1
27
13
7
10
14
93
118
74
37
-3
5
1
LT Debt
- -
- -
- -
- -
- -
- -
- -
1
1
- -
1
1
10
9
Total Equity
-2
-1
26
14
7
10
14
94
119
74
38
-3
-5
-7
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Common Equity (%)
- -
- -
- -
- -
- -
- -
- -
- -
-81.27
-149.81
- -
- -
- -
- -

Capital Structure

FRC

in mil. unless spec.
Sep'24
Dec'24
Mar'25
ST Debt
- -
- -
- -
LT Borrowings
10
10
8
LT Finance Leases
- -
- -
- -
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
1
2
3
Market Capitalization
7
4
3

Working Capital

FRC

in mil. unless spec.
Sep'24
Dec'24
Mar'25
Total Current Assets
10
10
7
Cash, Cash Equivalents & STI
- -
6
5
Accounts Receivable, Net
- -
- -
- -
Inventories
- -
- -
- -
Total Current Liabilities
10
4
6
Payables & Accruals
9
4
6
ST Debt
- -
- -
- -
Deferred Revenue
- -
- -
- -

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
43.88%
-22.24%
56.6%
Free Cash Flow
23.32%
15.57%
-19.36%
Net Income, GAAP
22.73%
12.92%
-50.34%
Sales/Revenue/Turnover
- -
- -
- -
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2023
- -
- -
- -
- -
- -
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2023
-66.49
-67.99
-52.87
- -
-227.43
2024
-22.02
-12.98
-11.24
- -
-36.38
2025
-2.61
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2023
- -
- -
- -
- -
- -
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -

Company Description

APIChat
CEO
William G. Rice
Full Time Employees
35
Sector
Healthcare
Industry
Biotechnology
Address
251 Consumers Road Toronto ON Canada M2J 4R3
IPO Date
Mar 16, 1992
Website
aptose.com
Business
Aptose Biosciences Inc. Aptose Biosciences Inc. is a clinical-stage biotechnology company focused on developing precision medicines that address unmet needs in oncology, particularly hematologic malignancies including acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and non-Hodgkin’s lymphomas (NHL); its small molecule cancer therapeutics pipeline features tuspetinib (HM43239 or TUS), an oral myeloid kinase inhibitor targeting key oncogenic pathways for relapsed or refractory AML, frontline triplet therapy with venetoclax plus azacitidine in newly diagnosed AML, and MDS; and luxeptinib (CG-806 or LUX), an oral dual lymphoid and myeloid kinase inhibitor that is mutation-agnostic against FLT3 and BTK for relapsed or refractory B-cell malignancies and AML resistant to approved targeted therapies. Originally incorporated as Lorus Therapeutics Inc. in 1986 in Toronto, Ontario, Canada, the company rebranded as Aptose Biosciences Inc. in 2014 with a strategic pivot to targeted kinase inhibitors for hematologic cancers and maintains headquarters in San Diego, California. Aptose operates primarily in North America with global clinical trial collaborations and recently entered into an arrangement agreement for acquisition by Hanmi Pharmaceutical Co. Ltd. announced on November 19, 2025, which supports continued advancement of the TUSCANY Phase 1/2 study for tuspetinib triplet therapy in AML while providing a premium to minority shareholders and marking Hanmi’s entry into North American operations.

Company News

APIChat
  • Aptose Reports First Quarter 2026 Results

  • Aptose Biosciences (TSE:APS) Stock Passes Above 50-Day Moving Average – Time to Sell?

  • Aptose Biosciences (TSE:APS) Share Price Crosses Above Fifty Day Moving Average – Time to Sell?

  • Aptose's Tuspetinib Triple Drug Therapy Featured at the 2025 ASH Annual Meeting; High Rate of Frontline Clinical Responses Continues Across AML Populations

  • Aptose Biosciences (TSE:APS) Shares Pass Above Fifty Day Moving Average – Should You Sell?

  • Aptose Announces Auditor Not Standing for Re-Appointment

  • Aptose to Present at the 2025 Bloom Burton & Co. Healthcare Investor Conference

  • Aptose Reports Year End 2024 Results and Corporate Highlights

  • Aptose Biosciences Meets Nasdaq Minimum Bid Price Compliance

  • Why Is Penny Stock Aptose Biosciences Trading Higher On Thursday?

  • Aptose Announces Positive Clinical Safety Review Committee (CSRC) Approval to Dose Escalate in Phase 1/2 Tuscany Trial of Frontline Triple Drug Therapy with Tuspetinib Amid Complete Responses and Favorable Safety in First Cohort

  • Aptose Announces Reverse Share Split

  • Aptose Enters into $25 Million Committed Equity Facility and Establishes New At-The-Market Facility

  • Aptose's Frontline Triple Drug Therapy with Tuspetinib Achieves Notable Responses in Newly Diagnosed AML Patients in the Phase 1/2 TUSCANY Trial

  • Aptose Announces First AML Patients Dosed with Tuspetinib Triplet Frontline Therapy in TUSCANY Trial

  • Aptose Announces Positive Decision by Nasdaq Hearings Panel

  • Aptose Announces Publication of Preclinical Data in AACR Journal Demonstrating Tuspetinib's Unique Mechanism of Action and Synthetic Lethality on AML Cells When Combined with Venetoclax

  • Aptose Clinical Data Featured in Poster Presentation at the 2024 ASH Annual Meeting Support Tuspetinib Triple Drug Therapy for Newly Diagnosed AML

  • Aptose Signs CRADA with NCI to Develop Tuspetinib for AML and MDS in Newly Launched MyeloMATCH Precision Medicine Trials

  • Aptose Biosciences Inc. Announces Closing of $8 Million Public Offering