- Business
- BioInvent International AB (publ) (Nasdaq Stockholm: BINV) is a clinical-stage biopharmaceutical company that discovers and develops novel, first-in-class immuno-modulatory antibodies for cancer immunotherapy, targeting hematological cancers and solid tumors through its proprietary F.I.R.S.T™ and n-CoDeR® technology platforms. The company's lead pipeline candidates include BI-1206, an antagonistic FcγRIIB-blocking antibody in Phase 2a trials for non-Hodgkin lymphoma (NHL) and planned for first-line non-small cell lung cancer (NSCLC) in combination with pembrolizumab; BI-1808, a first-in-class anti-TNFR2 agonist antibody in Phase 2a for solid tumors and cutaneous T-cell lymphoma; BI-1910, an anti-TNFR2 antibody in Phase 1 for advanced solid tumors; BI-1607, an FcγRIIB-blocking antibody in Phase 1/2a for HER2-positive solid tumors in combination with trastuzumab; and BT-001, an oncolytic virus in Phase 1 investigator-led trials. It generates revenues from research collaborations and license agreements with partners including MSD, AstraZeneca, Transgene, and CASI Pharmaceuticals; antibody manufacturing for third parties; and royalty interests, such as the May 2025 sale of mezagitamab (TAK-079) rights to XOMA Royalty Corp. for up to USD 30 million. BioInvent maintains a fully integrated manufacturing unit and operates clinical programs across North America and Europe.
Founded in 1996 and headquartered in Lund, Sweden, the company paused development of BI-1910 and BI-1607 in September 2025 to focus resources on BI-1206 and BI-1808, implementing a workforce reduction of approximately 25 positions while retaining preclinical capabilities for pipeline sustainability; this strategic shift extends cash runway into Q1 2027 pending key data readouts. Recent milestones encompass FDA IND approval for BI-1607 expansion to U.S. sites, EMA orphan drug designation and Japanese composition-of-matter patent for BI-1808, positive Phase 2a efficacy data for BI-1206 triple combination in relapsed/refractory NHL, and Clinical Trial Authorization for BI-1607 in solid tumors. It wholly owns subsidiary BioInvent Finans AB for warrant administration and reported Q3 2025 net sales of SEK 3.3 million with 122 employees as of year-end 2024.