ContraFect Corporation
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- ContraFect Corporation, formerly a clinical-stage biotechnology enterprise, specialized in the identification and advancement of therapeutic protein and antibody products designed to combat severe, drug-resistant infectious diseases. The company's primary focus centered on direct lytic agents, including lysins and amurin peptides, to offer novel treatment modalities. Its lead candidate, exebacase, a lysin, had progressed into Phase 3 clinical trials for addressing *Staphylococcus aureus* bacteremia, including instances of methicillin-resistant *Staphylococcus aureus* (MRSA). Further efforts included developing CF-296, an engineered lysin, aimed at invasive *Staphylococcus aureus* infections, such as those related to biofilms in prosthetic joints. Additionally, ContraFect was advancing CF-370, an investigational anti-bacterial lysin, through Phase 1 clinical studies for treating Gram-negative pathogens like *Pseudomonas aeruginosa*, associated with conditions such as hospital-acquired and ventilator-associated bacterial pneumonia. However, facing liquidity challenges, the company initiated Chapter 7 bankruptcy proceedings in December 2023. Subsequently, in March 2024, substantially all of ContraFect's intellectual property assets were acquired by Aurobac Therapeutics SAS through a Section 363 sale process. ContraFect Corporation was established in 2008 and previously maintained its headquarters in Yonkers, New York.
Why Is ContraFect (CFRX) Stock Up 23% Today?
ContraFect Announces FDA Clearance of CF-370 IND Application to Proceed With Phase 1 Clinical Study
ContraFect to Present at the ASM/ESCMID Joint Conference on Drug Development
ContraFect Announces Submission of IND Application to the FDA for its Development Candidate CF-370
ContraFect to Present at the World Anti-Microbial Resistance Congress 2023
ContraFect Reports Second Quarter 2023 Financial Results and Provides Business Update
ContraFect to Present New Data Demonstrating the Potential Efficacy of Its Engineered Lysins Against Antibiotic-Resistant Pathogens at ASM Microbe 2023
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ContraFect to Present Data Demonstrating the Potential of Its Direct Lytic Agents (DLAs) to Combat MRSA at ASM Microbe 2022