Operator
Hello, and thank you for standing by. My name is Lacy, and I will be your conference operator today.
At this time, I would like to welcome everyone to the Cytek Biosciences Third Quarter 2026 Earnings Conference Call. All lines have been placed on mute to prevent any background noise.
After the speakers' remarks, there will be a question-and-answer session. If you would like to ask a question during this time, simply press star followed by the number 1 on your telephone keypad.
If you would like to withdraw your question, press star 1 again. Thank you.
I would now like to turn the call over to Mark Meehan, Head of Investor Relations. Please go ahead.
Mark Meehan
Thank you, operator. Joining me today from Cytek are Wenbin Jiang, CEO, and Bill McCombe, CFO.
Earlier today, Cytek Biosciences released financial results for the third quarter ended September 30th, 2026. If you haven't received this news release, or if you'd like to be added to the company's distribution list, please send an email to [email protected].
A copy of the news release is also available on the Investor Relations section of Cytek's website at investors.cytekbio.com. Please note that we will be referencing a slide presentation during the call today that has been posted to the Investor section of our corporate website.
As a reminder, on slide 2, we will make statements during this call that are forward-looking statements within the meaning of the federal securities laws, including statements regarding Cytek's business plans, strategies, opportunities, and financial projections. These statements are based on the company's current expectations and inherently involve significant risks and uncertainties that could cause actual results or events to materially differ from those anticipated in these statements.
Additional information regarding these risks and uncertainties appears in our slide presentation in the section entitled Forward-Looking Statements, in the press release Cytek issued today, and in Cytek's filings with the SEC. This call will also include a discussion of certain financial measures that are not calculated in accordance with generally accepted accounting principles.
Additional information regarding our use of non-GAAP financial measures, including reconciliations to the most directly comparable GAAP financial measures, may be found in our slide presentation and in today's press release. While the company believes these non-GAAP financial measures provide useful information for investors, the presentation of this information is not intended to be considered in isolation or as a substitute for the financial information presented in accordance with GAAP.
This call will also provide a brief update about our active patent litigation. For more complete information about this case, as well as countersuits that we have instituted, please refer to our previous press release, as well as our SEC filings, including our Form 10-Q to be filed today.
Except as required by law, Cytek disclaims any duty to update forward-looking statements, whether because of new information, future events, or changes in its expectations. This conference call contains time-sensitive information and is accurate only as of the live broadcast, November 4th, 2026.
With that, I will turn the call over to Wenbin.
Wenbin Jiang
Thanks, Mark. Welcome, everyone, and thank you for your interest in Cytek.
On today's call, I will start with a discussion on our performance in the third quarter and review some business highlights before turning the call over to Bill for a detailed look at our financial results and our full-year outlook. Turning to slides 3 and 4.
We delivered another solid result in the third quarter with revenue of $53.2 million, an increase of 2% year-over-year. Our third quarter was highlighted by growth in the U.S.
driven by continued strong demand for our high-end, full spectrum profiling instruments, led by Aurora EVO, the double-digit growth in our service business, and by our robust gross margin performance. Growth in the third quarter was led by the U.S., where revenue grew 12% year-over-year to $30.4 million, continued strong momentum from the first half driven by instrument sales to academic and government customers and the continued service growth.
In EMEA, third quarter revenue was $12.5 million, up 1% year-over-year, a positive sign after a challenging first half that reflected improving instrument sales to academic and government customers. Total APAC revenue including China was $8.3 million, up 5% sequentially versus Q2, while being down 25% compared to a strong Q3 last year.
Turning to slide 5. The third quarter was highlighted by success at the high end, where our technology leadership continues to shine.
Customers are choosing Aurora EVO as it lets them run large panels and get consistent, reproducible data at higher throughput. The automation configurations we introduced last quarter further increased the value to customers with the API for automated plate handling systems fitting well into the high-volume workflows of biopharma and CRO customers.
Combined Aurora and Aurora EVO placements grew 23% year-over-year, with EVO placements nearly doubling year-over-year, reflecting robust demand for our next-generation platform. As a result of strong placements, high-end, full spectrum profiling instrument revenue grew 11%.
Across the broader business, we added a total of 140 instruments in the quarter, bringing our total installed base to 4,073 units. Borealis, our newest platform, which we introduced last quarter, is receiving strong interest from customers in both the academic and biopharma markets, and we doubled the size of our early access program during Q3.
As a reminder, Borealis is a seven-laser, full spectrum profiling cytometer with 50-color performance already demonstrated, and a clear path to go higher as new dyes and panels are developed. It will also include integrated imaging capabilities when we get to full commercial launch.
Paired with our new proprietary cFluor reagents, Borealis enables 60-color panels in a single tube, while also supporting nanoparticle analysis and higher sampling rates. Early access program customers are excited about how these capabilities can enhance insights and accelerate discovery in their labs.
We will continue to expand the early access program in the fourth quarter with a broader commercial launch planned for fiscal year 2027. Turning to slide 6.
During the third quarter, we launched a new Cytek Cloud analysis tool, the industry's first end-to-end platform that integrates the entire flow cytometry workflow, from panel design to data analysis, into one system. This will allow researchers to have a seamless experience, from experiment planning through data analysis, reducing the need to move between systems or recreate workflows.
Cloud analysis is available in the U.S. through Cytek Cloud Premium, a new subscription tier that adds cloud-based data analysis and online data storage.
The launch is an important milestone towards our vision of Cytek Cloud as a comprehensive digital ecosystem that supports flow cytometry workflows from beginning to end. As of the end of the third quarter, the total Cytek Cloud user base is approaching 30,000, up more than 20% since the start of the year.
Our recurring revenue base continued to grow in the third quarter. Combined service and reagent revenue was $19.1 million in Q3 2026 and represented 36% of Cytek's last 12-month revenue, up from 33% for the 12 months ended September 30, 2025.
We expect recurring revenue to represent an increasing percentage of total revenue over time. During the quarter, we also had important developments in our patent litigation case.
As we announced on August 21st, a jury in the U.S. District Court for the District of Delaware found in our favor on three of the four asserted claims, finding both no infringement and invalidity for each of those three claims.
On the fourth claim, the jury found no literal infringement, but did find infringement under the doctrine of equivalents. We do not believe that the applicable legal criteria for infringement under the doctrine of equivalents have been met.
We filed post-trial motions asking the court to overturn the verdict on this and other grounds, and we intend to pursue all available legal remedies. The jury's verdict does not require any change to our product offerings or operations, and our ability to sell and ship products is not affected.
Notably, the patent at issue is a U.S. patent and only applies to sales of instruments made in or imported into the United States.
Finally, I wanted to share an update on the new business unit structure we introduced earlier this year. After careful review, we have decided to postpone the implementation of these business units until the start of 2027.
We judged the near-term risk of moving to our new organizational structure midyear to be too significant. We remain confident that the new structure is the best way to support our long-term growth, but we recognized the critical need to deliver throughout the remainder of 2026.
We are continuing to focus resources and build out our teams to grow our clinical and solution-focused instruments and reagents. Stepping back, we were pleased with the overall performance of our business.
The third quarter was highlighted by continued success of our high-end Aurora EVO and Borealis analyzers, by the double-digit growth in our service business, and as Bill will detail shortly, the strong execution from our operations team, which resulted in our best third quarter gross margins since 2023. With top-line performance in line with our prior expectations, we are reiterating the midpoint of our full-year 2026 revenue guidance.
With that, I will now turn the call over to Bill for additional details on our Q3 financials and our full-year outlook.
Bill McCombe
Thanks, Wenbin. Turning to slide 7.
Third quarter revenue came in at $53.2 million, an increase of 2% compared to Q3 2025. A highlight for the quarter was the strong customer demand for our high-end analyzers with revenue growth of over 30% for the Aurora, Aurora EVO, and Borealis category.
This was the major factor driving U.S. total revenue growth of 12% and instrument growth of 9%.
EMEA revenue returned to modest total revenue growth of 1% year-on-year and instrument growth of 3% after two quarters of declines. APAC including China grew 5% sequentially compared to Q2, but was down 25% compared to a strong Q3 '25.
We saw particular strength in revenue from academic and government customers, which was up 38% year-over-year to $24.5 million, with strength across all regions. In the U.S., the largest region for the academic and government end market, instrument revenue grew more than 60%.
Biopharma, distributor, and CRO revenue declined approximately 17% year-over-year to $28.7 million against a strong Q3 last year. Product revenue, which is comprised of instruments and reagents, was $37.2 million, a decrease of 3% year-over-year, as strength in our high-end instruments was offset by declines in imaging and mid- to low-end instruments.
Service revenue grew 13% year-over-year, driven by growth in our installed base and continued active utilization of our systems. Turning to slide 8.
Turning to gross margin, as Wenbin mentioned, we had an outstanding result with GAAP gross profit of $31.2 million in Q3, representing a gross margin of 59% compared to 53% in Q3 2025, an increase of nearly 600 basis points, as we benefited from both higher product gross margin and higher service gross margin. Product gross margin increased 770 basis points to 61% compared to 53% in Q3 last year.
The increase was primarily due to lower overhead costs resulting from the completion of the transfer of manufacturing capacity from Seattle to Singapore, and also lower material costs and lower tariffs. Service gross margin was 53%, up from 51% in Q3 2025, reflecting service revenue growth of 13%, which outpaced the 8% increase in service cost of sales.
We are now realizing the full benefit of the transfer of manufacturing from our Seattle site to our Singapore facility earlier this year. This move is part of our region-for-region manufacturing strategy, which gives us lower-cost manufacturing capacity, greater supply flexibility, and helps mitigate tariff-related cost pressures.
Total operating expenses were $39.6 million in Q3, up 8% versus Q3 2025. Research and development expenses were $9.4 million, up 4%, while sales and marketing expenses were $11.9 million, up 2%.
General and administrative expenses were $18.4 million, up $2.2 million or 14% compared to Q3 2025. This was due to a $3 million increase in legal expenses associated with our patent litigation and specifically the trial, which occurred in August.
With the most expensive trial phase of this case behind us, we would expect our legal expenses to decline by $3 to $4 million in the fourth quarter compared to Q3. The loss from operations was $8.4 million in the third quarter compared to a $9.2 million loss in the year-ago quarter.
GAAP net loss was $6.1 million compared to a $5.5 million loss in the third quarter of 2025. The increase in GAAP net loss was due to a $1.5 million lower tax benefit, offset by a $0.8 million improvement in loss from operations.
Adjusted EBITDA, which excludes stock-based compensation and foreign exchange gains and losses, was $0.7 million in Q3 2026 compared to $2.5 million in Q3 2025. The decline was primarily due to lower investment income and higher operating expenses.
We anticipate adjusted EBITDA to improve meaningfully in the fourth quarter as revenue increases with our normal seasonal pattern. Cash, cash equivalents, restricted cash, and marketable securities totaled $256 million as of September 30, 2026, compared to $262 million as of June 30, 2026.
Our strong balance sheet continues to provide the financial flexibility to invest in our global growth priorities. Turning to slide 9.
We are maintaining the midpoint of our full-year 2026 revenue guidance while narrowing the range to $208 to $211 million. This assumes no change from current currency exchange rates.
This reflects year-to-date results and the growth outlook across our markets. In the fourth quarter, we expect revenue to be meaningfully higher than in the third quarter, consistent with our normal seasonality, driven by typical customer year-end purchasing patterns and continued growth in our service business.
For the full year 2026, we continue to expect adjusted EBITDA to be around breakeven, reflecting an anticipated strong fourth quarter result driven by the seasonal increase in revenue, as well as a meaningful decrease in litigation spending. With that, I will turn it back over to Wenbin.
Wenbin Jiang
Thanks, Bill. I want to close by thanking the entire Cytek team for their continued dedication and execution on behalf of our stakeholders.
Our third quarter was a solid one, and we expect a strong finish to the year. The results reflect the strength of our technology leadership in the flow cytometry industry.
Looking ahead, we feel well positioned heading into next year. We continue to gain share as our new product portfolio strengthens our technology leadership position in biopharma and academic research markets.
We also anticipate improving performance with clinical customers, driven by our new organizational structure and the benefits of our Sysmex collaboration in Europe. Finally, we expect to deliver improving profitability as we continue to drive leverage on increased volume and anticipate reduced G&A spend on lower litigation expenses.
Thanks to everyone for joining today's call. We will now open it up for questions.
Operator
At this time, I would like to remind everyone in order to ask a question, please press star 1. Your first question comes from the line of Mason Carrico with Stephens.
Please go ahead.
Harrison Parsons
Hey, this is Harrison on for Mason. Thanks for taking the questions.
Could you just start by walking us through the guidance range for 2026? Should we expect service revenue to continue to grow around the low-double-digit clip in the fourth quarter, and product revenue to make up the balance there?
Bill McCombe
Yeah. Our service revenue has grown fairly consistently, we'd expect that to continue and at similar rates to recent quarters.
The product revenue would make up the balance. That's right.
Harrison Parsons
Got it. Then looking ahead here at 2027, I think you previously pointed to the second half '26 growth rate as a fair jumping-off point for next year.
Does that framework still hold today? How are you thinking about growth next year across the different geographies?
Bill McCombe
I don't think we've commented specifically on giving guidance for growth in 2027. I'm not going to comment on your framework there.
What I will say is that we will continue to advance, and we'll give more specific guidance when we announce Q4 revenue in late February, early March. We would expect to outgrow the market in 2027.
We are continuing to invest in our high-end product portfolio. We're going to, as bring to market the Borealis analyzer with full imaging capability.
That's slated for launch in 2027. We are investing substantial resources in growing our low- to mid-range instruments and our reagent portfolio.
We'll maintain leadership in the high end, and we'll invest in growing our business. We would expect improving profitability.
I can't really give more specific guidance beyond that. Based on those investments and based on our performance so far, we would expect to outgrow the market and outgrow our peers.
Operator
Your next question comes from the line of Chad Wiatrowski with TD Cowen. Please go ahead.
Chad Wiatrowski
Hey guys, continued taking market share next year, plan to outgrow the market. Do you still feel like the market's maybe flat, or do you think we've returned to growth here across end markets?
Bill McCombe
I think the market growth has been better, really going back to the fourth quarter of last year and the first three quarters of this year. We've certainly done better than the early part of 2025.
The market has been better. Some of the headwinds that occurred back then have abated.
I think we feel that the market environment is generally positive.
Chad Wiatrowski
Thanks. Then I guess on the Cytek Cloud user base, the growth's pretty impressive.
Just wondering, if internally, do you guys view that as maybe more of a moat to your instruments as these tools are used more broadly across workflows? Or is this something you think, I know you started to maybe monetize it a little bit previously, but do you feel like there's a lot of juice to squeeze here, and maybe that could be upside to service revenues?
Wenbin Jiang
The intention of Cytek Cloud is not to really squeeze any profit out of the platform by itself, right? It is a tool to enable our user to leverage our full solutions, including our instrument, reagents, and panel design, data analysis all together, customers will stay with what we have.
Chad Wiatrowski
Thanks for the questions, guys.
Operator
Your final question comes from the line of David Westenberg with Piper Sandler. Please go ahead.
Skye Gilbert
Hi, this is Skye on for Dave. Thanks for taking the questions.
Maybe first, can you just talk a bit more about biopharma? You've seen some growth in the past from large pharma and biotech customers.
I know you called out the tough comp this quarter, but has the momentum slowed at all? What does that mean for CROs and some of the smaller customers?
Ultimately, how much of the demand now is reflecting ongoing fleet deployments versus individual instrument purchases?
Bill McCombe
I would point out that year to date, biopharma is up 3%. Look, it's generally been lumpy.
We did have some strong quarters towards the back end of last year. The other factor that influences our numbers as reported is that a disproportionate, much higher share of overall sales in Asia-Pac and China go through distributors, which we report in the biopharma, CRO, and distributor category.
As I think we noted, the markets in APAC and China in the third quarter were quite a bit weaker, primarily due to macroeconomic factors in those markets. That has sort of dampened the growth of what we report as the biopharma, CRO, distributor category.
I think it's important to bear that in mind. We think the biopharma sector, particularly in the U.S., that they have money available for a year-end budget flush.
We think that the Aurora Evo, because of its high throughput and its automation capabilities, is an excellent product for that market. We remain generally quite positive on that market segment.
Skye Gilbert
Very helpful, thanks. Just lastly, in September, I think for a few of the instruments, you mentioned you were selling everything you could make and that orders were generally booked and shipped within the quarter.
Where are you still supply constrained? Are there lead times or ordering patterns or other cancellations giving you better visibility into demand at this time?
Thanks.
Bill McCombe
Other than for small amounts, we generally ship everything that we book within a quarter. When we made those comments on the Q2 call, we were talking about Borealis and the Aurora Evo with the enhanced automation capability.
We're continuing to increase our production rate of those types of systems. We expect them to be important contributors going forward.
Products that are seeing good, very good demand from customers. Supply constraints is not a big issue for us.
Operator
There are no further questions at this time.
Mark Meehan
Thanks. We will go ahead and end the call there.
Thank you, everyone, for joining, and please reach out to us if you have any follow-up questions. Bye.
Operator
Ladies and gentlemen, you may now disconnect.