- Business
- Fennec Pharmaceuticals Inc. (TSX: FRX) is a commercial-stage biopharmaceutical company focused on developing and commercializing therapies to mitigate chemotherapy-induced toxicities in pediatric cancer patients; its lead product, PEDMARK (sodium thiosulfate injection), is FDA-approved to reduce the risk of ototoxicity associated with cisplatin chemotherapy in patients one month and older with localized, non-metastatic solid tumors. PEDMARK, marketed as PEDMARQSI in certain regions, is administered intravenously post-cisplatin infusion and targets pediatric oncology patients undergoing treatment for solid tumors; the company sells through regional pediatric oncology specialists, medical science liaisons, field-based teams, and distribution partners. Incorporated in 1996 and headquartered in Research Triangle Park, North Carolina, with additional operations in Canada, Fennec conducts business primarily in the United States, Europe, the United Kingdom, Australia, New Zealand, Turkey, and Gulf Cooperation Council countries via strategic alliances. Recent developments include a March 2024 exclusive licensing agreement with Norgine Pharmaceuticals Ltd. for PEDMARQSI commercialization in Europe, the UK, Australia, and New Zealand, where it is now available in the UK and Germany; a partnership with Inpharmus for distribution in Turkey and Gulf countries; full repayment of approximately $32 million in convertible debt by November 2025, following a $13 million early repayment in December 2024; achievement of $29.6 million in full-year 2024 PEDMARK net product sales, up 40% year-over-year, with Q4 2024 sales at $7.9 million and Q2 2025 sales up 33%; and a $5.025 million funding receipt in November 2025 alongside key management hires to enhance commercial execution in academic centers and community practices.