- Business
- Oxurion NV (Euronext Brussels: OXUR) is a biopharmaceutical company focused on developing next-generation therapies to preserve vision in patients with retinal disorders, including geographic atrophy and age-related macular degeneration; it employs a CRISPR-based target discovery platform to identify cytoprotective targets beyond traditional complement pathways, advancing preclinical programs toward multi-specific lead candidates for geographic atrophy. The company offers innovative treatments addressing unmet needs in ophthalmology, with expertise spanning retinal diseases such as wet and dry AMD, diabetic macular edema, and vitreomacular adhesion; it previously commercialized Jetrea (ocriplasmin), the only approved pharmacological vitreolysis drug, licensed worldwide to Inceptua Group through 2023. Founded in 1991 as ThromboGenics NV and renamed Oxurion NV in 2018, Oxurion maintains headquarters in Leuven, Belgium, with wholly owned subsidiaries ThromboGenics Inc. in New York, USA, Oncurious NV and Oxurion France SAS in Leuven and Toulouse respectively; operations center on R&D at its GMP-certified Bio-Incubator facility in Leuven, targeting markets in Europe and North America through a strategy blending internal innovation with healthcare sector acquisitions. Recent strategic shifts include a comprehensive restructuring in partnership with Atlas Special Opportunities LLC, securing committed but conditional funding up to 20 million euro via convertible bonds to support operations through 2025 amid share consolidation in September 2024; in August 2025, Oxurion acquired 72% of Axiodis CRO, a French biometrics and clinical data management specialist with proprietary eCRF platform, financed by Atlas and aligning with ambitions to build an integrated clinical trial platform as a one-stop shop for clients from trial design to market access. In October 2025, Oxurion signed a letter of intent for an additional CRO acquisition emphasizing clinical operations, regulatory affairs, medical affairs, scientific communication, and market access, with exclusivity through December 31, 2025 and ongoing due diligence to create synergies with Axiodis; discussions on a prior preclinical target ended in November 2025 to prioritize financial discipline and high-value clinical integration, reinforcing focus on revenue-generating European subcontractors in clinical development.