- Business
- GeneTether Therapeutics Inc. (CSE: GTTX, OTC: GNTTF), formerly focused on genetic medicines, now develops oncology therapies following its January 2025 name change to Rize Oncology Inc.; headquartered in Kelowna, British Columbia, Canada, and founded in 2018, the company operates in the biopharmaceutical sector targeting rare cancers and proliferative diseases. Core offerings center on STS-201, a small-molecule drug candidate exclusively licensed from EGB Ventures in late 2024, which blocks cell division at the late G2/M boundary to enhance radiation sensitivity, normalize tumor vasculature, improve oxygenation, and reduce metastasis in soft tissue sarcoma (STS) and other cancers; the prior proprietary GeneTether platform technology for high-efficiency genome editing and gene correction remains part of its foundational intellectual property, including U.S. patents granted in 2022. Recent strategic shifts include the October 2024 binding term sheet for the STS-201 license and a C$250,000-C$500,000 private placement financing, both approved by shareholders in December 2024; engagement of John Rothman, Ph.D., as consulting Chief Scientific Officer with over 30 years in drug development; and laboratory expansion in the Bay Area in 2022 to accelerate R&D, reflecting a pivot from broad genetic therapies to oncology-focused assets with potential Orphan Drug status for STS.