Operator
Ladies and gentlemen, welcome to the Sartorius and Sartorius Stedim Biotech conference call and live webcast on Q1 2026. I'm Moritz, your Chorus Call operator.
I would like to remind you that all participants will be in a listen-only mode, and the conference is being recorded. A replay will be available shortly after the call.
The presentation will be followed by a question-and-answer session. You can register for questions at any time by pressing star and 1 on your telephone.
For operator assistance, please press star and 0. The conference must not be recorded for publication or broadcast.
I would now like to turn the conference over to Petra Müller, Head of Investor Relations of Sartorius. Please go ahead.
Petra Müller
Thank you. Hello and a warm welcome also from my side.
I'm joined today by our CEO, Michael Grosse, by Florian Funck, our CFO, by René Fáber, Head of the Bioprocessing division and CEO of Sartorius Stedim Biotech, and by Alexandra Gatzemeyer, Head of our LPS division. As always, we will start with prepared remarks, followed by the Q&A session.
As the call is scheduled to 1 hour, please limit your question to one so that as many participants as possible can take part. Please note that management comments during this call will include forward-looking statements that involve risks and uncertainties.
For a discussion of risk factors, I encourage you to review the Safe Harbor statement contained in today's press release and the presentation. With that, I'm pleased to hand over to Michael Grosse, CEO of Sartorius.
Michael, please go ahead.
Michael Grosse
Thank you, Petra, and a very warm welcome from my side as well. We are happy with the start of 2026, which is again sort of a transition year.
Before turning to the key messages for the quarter, I would like to briefly reflect on the strategic context following our Capital Markets Day a few weeks ago. At the CMD, we provided an update on our strategy and outlined our new mid-term financial targets.
Since then, the focus has been and is very clearly shifting to execution. The real work begins by consistently translating strategy into tangible results and actions, and the work has already started in line with the evolving needs of our customers and the broader biopharma and life science markets.
Our shared vision remains unchanged: to simplify progress in biopharma and life science research, enabling better health for more people. With that context in mind, let me now turn to the key messages we would like to share with you today.
We're off to a good start in 2026 and are very pleased with our performance in the first quarter of the year. Sales developed well, with a continued strong recurring business in both divisions.
At the same time, underlying EBITDA developed positively year-on-year, and profitability remained resilient. This once again underlines the strength and resilience of our business model, as well as the benefits of our disciplined operational execution.
In Bioprocess Solutions, sales increased by around 8%, reflecting robust underlying demand. Consumables momentum remained strong, while equipment was soft as expected, but is anticipated to improve in Q2.
Lab Products & Services showed around 5% sales growth, continuing the positive momentum that started in the second half of 2025 already. This development was driven primarily by lab consumables and our bioanalytical portfolio, also including the Mactec acquisition.
While instruments demand remains cautious overall, we continue to expect at least stable development in 2026. Cash flow development was strong year-on-year.
At the same time, we continue to make progress on deleveraging, underlining our clear commitment to financial discipline and a strong balance sheet. In light of our solid start into the year, we confirm our full-year 2026 guidance for the group, and we expect sales revenue growth in constant currencies of around 5% to 9% and an underlying EBITDA margin slightly above 30%.
Let me now briefly highlight a few innovations launched in Q1 that demonstrate the strong customer demand for Sartorius solutions across the biologics value chain, starting with cell therapy manufacturing. With Iviro, our new cell therapy manufacturing platform, we are addressing one of the key bottlenecks in autologous cell and gene therapy: scalable and reliable manufacturing of highly personalized therapies.
Iviro enables fully automated multi-parallel production, allowing customers to run up to eight patient batches in parallel and achieve up to four times higher yield compared to conventional approaches. By automating critical process steps and reducing manual handoffs, Iviro also shortens manufacturing cycle times, helping customers move faster from vein to vein and ultimately accelerate time to patient.
At the same time, Iviro helps to reduce footprint, capital intensity, and overall manufacturing complexity, supporting both centralized and decentralized production models. Turning to cell line development, we introduced two complementary innovations aimed at significantly improving speed and efficiency early in the biologics development.
The latest generation of our CellCelector platform, the CellCelector CLD for cell line development, enables significantly faster and more reliable cell line development by combining automated imaging, monoclonality verification, and gentle clone isolation in one single system. This reduces manual efforts and uncertainty early in the development, shortens timelines from months to weeks, and strengthens regulatory readiness through integrated documentation and traceability.
In parallel, our genetically engineered CHO host cell line allows for faster clone development and up to three times higher productivity, supporting robust and scalable manufacturing as biologics pipelines continue to grow in complexity. These innovations once again highlight how Sartorius systematically removes bottlenecks across the biologics value chain, from early development to manufacturing, by helping customers shorten timelines, increase yields, and improve overall process efficiency and cost structures.
With that, I now hand over to Florian to walk you through our Q1 financials in more detail.
Florian Funck
Thank you, Michael, and a warm welcome from my side as well. I'm happy to take you through our numbers that reflect the continuation of consistently strong performance from the year 2025 into 2026.
Let me begin with top-line performance at group level. In the first quarter of 2026, sales revenue increased by 7.5% in constant currencies and 1.8% reported, reaching €899 million.
Looking now at our divisions in more detail: in Bioprocess Solutions, sales increased by 8.1% in constant currencies and 2.4% reported, reaching €735 million. Growth was driven by the high-margin recurring consumables business.
Equipment performed in line with expectations, with a softer Q1 due to delivery schedules of customers and revenue recognition more loaded towards Q2. We anticipate stronger Q2 equipment sales and expect BPS equipment to deliver at least prior-year levels in H1 in constant currencies, supporting a healthy first-half performance.
In Lab Products & Services, sales increased by 4.9% in constant currencies, reaching €164 million. Mactec contributed 2.8 percentage points to LPS growth in constant currencies, and based on reported figures, LPS posts a slight sales decline of -0.6%, which is purely FX-related.
Growth was driven by a robust contribution from our recurring business, supported by positive momentum in our bioanalytics portfolio. Let me also quickly elaborate on our regional performance.
Overall, the first quarter showed healthy growth momentum across all regions, supported by continued strength in consumables. Starting with EMEA, sales increased by 8.0% in constant currencies in the first quarter.
In the Americas, sales grew by 6% in constant currencies, and the growth was solid, particularly considering the stronger comparison base from last year. Asia-Pacific delivered the strongest regional performance, with sales growth of 8.9% in constant currencies, with China contributing nicely to the region's BPS growth.
Let me now turn to profitability, which deserves a bit more explanation given the offsetting dynamics in the first quarter. The group's underlying EBITDA increased slightly by 1.6% to €267 million in the period from January to March compared to prior year.
Positive volume effects and economies of scale were offset by mix effects within BPS consumables and tariff impacts, as well as continued investments in future growth initiatives, especially in LPS. Against this backdrop, the corresponding EBITDA margin remained resilient at 29.7%, almost fully absorbing negative tariff effects of around 40 basis points.
Similar developments as on group level were also recognized at divisional level. In Bioprocess Solutions, the underlying EBITDA margin developed positively.
Margin expansion was driven by increased volumes and operating leverage, overcompensating tariffs and some mix effects within consumables. As a result, underlying EBITDA increased to €233 million, and the margin improved by 30 basis points to 31.8% in the quarter.
In Lab Products & Services, as already flagged in early February, we are executing a multi-year investment program to scale future growth areas. This is already well reflected in our margin development over the past couple of quarters and is fully in line with our full-year 2026 expectations.
Consequently, the underlying EBITDA margin was 20.7%, unchanged compared to the level in Q4 2025, and also, of course, negatively impacted by tariffs. Now let us look at performance below underlying EBITDA, where both net profit and free cash flow developed well in the first quarter.
The development of underlying net profit is mainly driven by the same effects we discussed at the underlying EBITDA level. On top of that, it is also mirroring higher depreciation caused by our CapEx programs over the past few years, as we highlighted at our Capital Markets Day a few weeks ago.
While depreciation effects are recognized immediately with go-live of a building, as usual, the corresponding volume revenue contributions materialize progressively as the additional capacity utilization is ramped up. Furthermore, we saw financing costs slightly increasing as cheap financing from early pandemic times ran out in H2 2025.
Reported net profit increased by 16% year-over-year to €56 million, thanks to lower extraordinary items that were last year mainly driven by our S/4HANA changeover, and we talked about this also at Q1 conference call '25. As these extraordinaries are excluded from our underlying profit KPIs.
Turning to cash-related items, operating cash flow increased strongly to €189 million, up almost 36% year-on-year. This improvement was driven by €20 million higher reported EBITDA and lower tax payments versus high prior-year base, compensating for the growth-related increase in working capital.
Looking at working capital, I would like to emphasize that the working capital dynamics can mainly be explained by higher accounts receivable at quarter-end, reflecting strong sales activity towards the end of the quarter. Customers received shipments and were invoiced late in the quarter, but due to timing effects and the Easter holiday season, many of these invoices had not yet converted into cash by quarter-end and therefore sitting in AR.
Based on the higher operating cash flow and relatively constant CapEx spending, also free cash flow increased significantly to €113 million. The CapEx ratio of 8.6% was at prior-year level, reflecting continued disciplined investments in support of future growth, but we continue to expect full-year CapEx of around 12.5% of sales for the full-year period.
To conclude our discussion of the first-quarter financials, let me briefly turn to our balance-sheet-related key figures. We maintained a solid equity ratio of 39.4% at the end of the first quarter.
The slight change compared to year-end reflects the dividends already offset from equity after the AGMs of Sartorius AG and Sartorius Stedim Biotech S.A. in March 2026.
Net debt decreased slightly to €3.727 billion, reflecting continued deleveraging despite ongoing investment activity. At the same time, we continued to actively manage our gross debt profile.
This makes the reduction in net debt particularly notable, as it was achieved despite the dividend payout to Sartorius AG shareholders for fiscal year 2025 on March 31st, underscoring our continued focus on disciplined deleveraging. As a result, the leverage ratio, defined as net debt to underlying EBITDA, improved slightly to 3.53 times, down from 3.55 times at year-end 2025, and this confirms that we are progressing as planned on our deleveraging path.
Taken together, these developments underline our continued commitment to financial discipline and to maintaining a strong investment-grade credit profile. With that, I would like to hand back over to Michael.
Michael Grosse
Thank you, Florian. Based on the solid performance in the first 3 months of the year and the overall market development, we are confirming our full-year 2026 guidance and continue to view 2026 as a transition year toward our mid-term ambitions as outlined at our Capital Markets Day in March.
For Sartorius Group, we expect sales revenue growth in constant currencies of around 5% to 9%. For Bioprocess Solutions, we anticipate growth within a range of approximately 6% to 10%, primarily driven by recurring business, while the equipment business is expected to remain at least stable.
In Lab Products & Services, we expect sales growth of around 2% to 6%, reflecting continued strength in the recurring business and a stabilizing instruments environment. At group level, sales growth includes around 1 percentage point contribution from the Mactec acquisition and the US tariff-related surcharges, while LPS revenue growth includes approximately 1.5 percentage points from Mactec.
Turning to profitability, we expect the underlying EBITDA margins to be slightly above 30% for the group. For Bioprocess Solutions, the margin should be slightly above 32%, while in Lab Products & Services, we expect the margin to be slightly below 21%.
The CapEx ratio is expected to remain around prior-year levels as we continue to invest selectively and with discipline in our global research and manufacturing footprint. We also expect net debt to underlying EBITDA to decrease to slightly above 3 times by year-end, reflecting our continued focus on deleveraging, as Florian said before.
Given the recent volatility in FX rates, we would also like to share some additional color on the expected foreign exchange impact for the second quarter. We currently anticipate a headwind in the region of -2.5 percentage points in Q2, respectively -4 percentage points for H1 cumulated, while we continue to expect FX effects for the full year to be around -2 percentage points.
We remain mindful of an increasingly complex external environment. Current geopolitical tensions, particularly in the Middle East, are driving increased uncertainty, especially the longer this situation persists.
However, we feel comfortable with our guidance as defined in early February and reiterated today. We expect the second half of the year to be stronger than the first half in absolute numbers.
Our confidence is based on the positive underlying development of the biopharma market, a strong order book, and our ability to navigate the continued volatility and uncertainty caused by the geopolitical and macroeconomic tensions. Looking ahead, Sartorius has a clear vision and strategy, and we are firmly committed to executing it with discipline, consistency, and a long-term perspective to deliver sustainable value creation.
With that, I would now like to hand over to René, who will walk you through the financials of Sartorius Stedim Biotech in more detail. René.
René Fáber
Thank you very much, Michael. Also from my side, welcome and thank you for joining our Q1 results call today.
Sartorius Stedim Biotech delivered a strong start into 2026, supported by our high-margin consumables business as well as continued operating leverage. In the first quarter of 2026, sales revenue increased by 7.9% in constant currencies, reaching €762 million.
Growth in reported currencies amounted to 2.3%. Our recurring consumables business was fueled by strong underlying demand.
Equipment, as Florian mentioned before, performed in line with our expectations, with a softer Q1 due to the delivery schedules of customers and revenue recognition more geared towards Q2. We anticipate stronger Q2 equipment sales, which should deliver at least prior-year levels in H1, supporting a healthy first-half performance.
Looking at profitability, we observed similar developments to those at Sartorius AG, as Florian elaborated earlier on. While earnings continue to improve in the first quarter, the underlying EBITDA margin remained largely flat.
Positive volume effects and economies of scale were offset by a less favorable product mix within the consumables portfolio and tariff impacts. Additionally, it has to be noted that there was a technical margin drag of 25 basis points due to an increase of the Sartorius brand name fee charged from Sartorius AG to SSB.
As a result, underlying EBITDA increased to €233 million, and the margin remained resilient at 30.7% for the quarter. Looking at the regional performance, all regions contributed to positive business development in the first quarter, supported by continued strength in consumables.
Starting with EMEA, sales increased by 9.1% in constant currencies. In Americas, sales grew by 5.6% in constant currency, reflecting a tougher prior-year comparison, but remaining positive overall.
Asia-Pacific delivered the strongest regional performance, with sales growth of 9.4% in constant currencies, with China contributing nicely to the region's growth. Looking now at net profit and cash flow, profitability and cash generation developed solidly over the year.
Starting with earnings before EBITDA, all metrics improved slightly. Underlying net profit increased slightly disproportionately to underlying EBITDA, mirroring higher depreciation caused by our CapEx program over the past few years.
Reported net profit improved by 3% to €88 million, thanks to lower extraordinary items, which are excluded from the underlying profitability measures and were therefore supportive. Turning to cash-related items now, operating cash flow increased strongly to €193 million, up more than 61% year-on-year, driven by higher EBITDA and lower taxes, compensating for the gross-related increase in working capital.
As a result, free cash flow rose significantly to €124 million, supported by the strong operating cash flow and stable CapEx at the prior-year levels. Accordingly, the CapEx ratio increased slightly to 9.1%, reflecting continued disciplined investments in support of future growth, but we continue to expect full-year CapEx of around 13% of sales for the full-year period.
A quick look at our balance sheet metrics. At the end of the first quarter, we continued to show a very strong equity ratio of 50.6%, reflecting our solid capital structure.
Compared with year-end, the slight decrease mainly reflects the dividend, which was offset from equity following the AGM end of March. Net debt decreased slightly, and the ratio of net debt to underlying EBITDA progressed as planned.
The net debt to underlying EBITDA ratio improved further to 2.28 times, down from 2.38 times at year-end, confirming that we remain well on track on our deleveraging path. Overall, these developments underline a strong balance sheet position of Sartorius Stedim Biotech and provide a solid foundation to support future growth while maintaining financial flexibility.
Before we move into Q&A, let me quickly elaborate on our confirmed outlook for full-year 2026. Based on the solid performance in the first 3 months and the over a year and overall market development, we are confirming our full-year 2026 guidance.
We expect to stay on our profitable growth path, and for 2026, sales revenue growth in the range of 6% to 10% in constant currencies, including 1 percentage point contribution from US tariff surcharges. Growth will be mainly driven by recurring business, but again against higher comps, while the equipment business should remain at least stable.
Based on our order book, we continue to expect a stronger second half compared to the first half at Sartorius Stedim Biotech. This reflects the expected gradual normalization and improvement in the equipment business throughout the year.
The underlying EBITDA margin should increase to slightly above 31%. Our CapEx ratio is expected to stay around previous-year level of around 13%, reflecting our ongoing investments into research and resilient production footprint.
Our commitment to deleveraging remains unchanged. We anticipate the leverage ratio, the net debt to underlying EBITDA, to decrease slightly to slightly above 2 times at year-end.
Given the volatility we have seen in the currency exchange rates over the past few years few months, let me also share some FX assumptions for the Sartorius Stedim Biotech Group. We currently anticipate a headwind of approximately -2.5 percentage points in the second quarter, while we continue to expect FX effects for the full year to be around -2 percentage points.
As Michael highlighted earlier for Sartorius AG, and without repeating this in detail, the same considerations also apply to Sartorius Stedim Biotech. We feel comfortable with our guidance as defined in early February and reiterated today.
Our confidence is based on positive underlying development of the biopharma market, our strong order book, our ability to navigate the continued volatility and uncertainty driven by geopolitical and macroeconomic tensions. With this, I will hand over to the operator to begin the Q&A session.
Operator
Ladies and gentlemen, we will now begin the question-and-answer session. Anyone who wishes to ask a question may press star and 1 on their telephone.
You will hear a tone to confirm that you have entered the queue. If you wish to remove yourself from the question queue, you may press star and 2.
Questioners on the phone are requested to disable the loudspeaker mode and eventually turn off the volume from the webcast while asking a question. In the interest of time, please limit yourself to one question.
Anyone who has a question may press star and 1 at this time. The first question comes from Zain Ebrahim from J.P.
Morgan. Please go ahead.
Zain Ebrahim
Hello, Zain Ebrahim, J.P. Morgan.
Thanks for taking my question. I'll stick to one.
My question is on the demand activity you're seeing at the moment in equipment. Can you comment on what the latest is from customers based on your latest conversations with them?
Thanks very much.
René Fáber
Thank you for that question. Let me first reiterate what we have just explained, how the equipment is developing.
For Q1, we have seen a softer development in sales, more or less as expected, and we see the revenue recognitions being moved or was moved more towards the Q2. What we anticipate to see for the H1 is, first of all, stronger Q2 equipment sales, and H1 to be then at least at the level of the prior year.
Overall, I would say equipment develops as we have expected. The positive start in the year coming from a quite strong, relatively strong H2.
We have seen already in H2 last year, Q3, Q4 particularly, were quite positive quarters in equipment, and we're benefiting from that in the beginning of the year as well. Overall, we are confirming our view on the equipment moving forward.
As I said, H1 positive, at least at the prior-year level, and same for the full year. Overall, H2, as we can say today, we would expect, based on the discussions we have with customers and the funnel we see, which is positively developing as well, H2 we expect to be stronger than H1 from today's perspective.
Zain Ebrahim
Thanks a lot. Then
Operator
the next question comes from Doug Schenkel from Wolfe Research. Please go ahead.
Doug Schenkel
Thank you for taking the question. It sounds like you expect bioprocessing equipment growth in Q2, which I think is what you were clarifying in the last question, but I just want to make sure that's right.
I want to also confirm that, based on trends and backlog, that you're expecting bio equipment growth to continue into the second half. Then I guess the last part to this question would be, are there any areas that you would call out that are notably driving a recovery in equipment, and conversely, are there areas that you're still awaiting some recovery?
Thank you.
René Fáber
Yeah. Absolutely.
Thanks for the question. Confirming, yes, we're expecting Q2 growth in equipment sales, as I mentioned.
Also, I think second part of your question was H2 above H1, that's our current view indeed. Where is this happening, how is overall equipment developing looking at different parts of the portfolio or regions, honestly, I think it's quite all over the place.
We don't see really a special pockets of growth or still-muted development. Definitely have seen a good traction on bioreactors.
Now, as you remember, we talked about the consumption of bags and consumables, which we see going with the equipment, that is still well on track and continues nicely growing. Here and there, we see already new installations happening.
I mentioned bioreactors, but it's going also in downstream. Very successful initial placements of our new innovative Bionic platform supporting process intensification as well.
Some larger projects in area of peptides, in chromatography, it's kind of cross the board. Then
Operator
the next question comes from Subbu Nambi from Guggenheim Securities. Please go ahead.
Subbu Nambi
Hey, guys. Good morning.
At the Capital Markets Day a few weeks ago, you mentioned that biotech has been improving. The capital markets environment remains strong for biotech.
Are you seeing any change in behavior, and is that a potential source of upside relative to your full-year targets if trends continue?
Michael Grosse
I may start just briefly. As indicated there at the Capital Markets Day, the funding environment has improved progressively in the second half of the year.
Towards year-end, we already could see some more activities and interest and lead generations as well from the biotech side. I think overall, if we look now as well at the LPS portfolio, remains probably still on a rather stable and lower levels.
At the same time, now as we've said, I think as we expect overall order situation, opportunity generation for the second half of the year to be a great foundation. Again, given the lead times for these orders that will be generated as well from that part of the business, again, I think we need to be mindful that early realization of those sales will be rather the very tail end of 2026, and rather create now the potential bench for revenue realization in 2027.
Subbu Nambi
Thank you.
Operator
The next question comes from Charles Pitman-King from Barclays. Please go ahead.
Charles Pitman-King
Hi, guys. Thanks very much for taking my questions.
I apologize if I missed this clarification, but just coming back to your 2H being greater than 1H on both an equipment-specific and a broader BPS dynamic, can you just confirm that what you're expecting when you say absolute is actually a continued growth in the organic line, or is this primarily reflecting the removal of the FX headwind? Is that what gives you the confidence of absolute being greater in 2H than 1H?
Just trying to get an idea that the equipment sales are in fact expected to improve over the course of this year. Thank you.
Florian Funck
Charles. First, let me talk to the question regarding FX.
All that we are talking here, which is sales-related, is FX-corrected, it's in constant currencies. Yeah?
What we have been saying is that we are expecting a higher H2 versus H1 in absolute million euro currency-adjusted. Right.
Charles Pitman-King
Just in terms of the organic growth rate on equipment in the second half? Sales versus orders?
Florian Funck
No, we've said that we are expecting H1 sales currency-adjusted to be at least on the level of prior year. Still also for the full year, we've said that we're expecting full-year equipment sales to be at least on prior-year levels.
Charles Pitman-King
Perfect. Thank you.
Florian Funck
Welcome.
Operator
The next question comes from Charlie Haywood from Bank of America. Please go ahead.
Charlie Haywood
Thanks. Charlie Haywood, Bank of America.
A question on BPS consumables, actually, and the contribution to the guide. I think René, at the full year, suggested low-teens consumables growth is a reasonable expectation for a normal year, and then you haven't called out many specific headwinds to the consumable side other than acknowledging '25 is a tougher comp.
Then obviously tariffs is actually a slight tailwind to that. Is it fair to think, of all of those factors, that consumables growth in the roughly low-teens range for this year would be a sensible answer?
Florian Funck
Let me tackle that, Charlie, and René maybe to comment on that. Please bear in mind we have said that the year '26 is a transition year.
Please do not apply the kind of normal growth rate that we've given in the mid-term guidance also as the kind of anchor point for the year '26. Additionally, on top of that, I think what we also set clearly is that we are expecting clear base effects because of the very high comps, so that growth rates that we've seen in the year '25, where it was in the teenish area, is not one-by-one to be expected to continue.
It will be still a healthy and strong growth, that is our expectation, but I think it would be wrong now to nail us down on a double-digit consumables growth for the full year.
Charlie Haywood
Thank you. Then
Operator
the next question would come from Charles Weston from RBC Europe. Please go ahead.
Charles Weston
Thanks for taking the question. In terms of China, you and René, both spoke quite constructively at the Capital Markets Day, saying that there's more activity and recovery from China companies looking to expand globally.
I think one of your US peers reported double-digit growth in China bioprocessing in Q1 and said it was in recovery mode. Can you just perhaps give us any further color about what you're seeing from that market in Q1 and in Q2 so far, please?
Michael Grosse
Yeah. I can get started.
As outlined, I think overall we are encouraged to see that there is a growth contribution from China after two rather difficult and really weak years overall. I think I still would like to make the comment upfront that the tendency that we see and a bit the muted demand when it gets to the equipment and instruments business, that remains there, and hence with a bigger impact that we have in that business fitly for the Lab Products & Services division.
It is indeed the fact that here the contribution is lower and it remains rather soft on that side. However, I would say it's great to see the Q1 development there on the BPS and consumable business side, where we basically seen overall group-level performance of around, close to 30% on that basis.
On this perspective, we take a look that the growth contribution overall from China is positive on the consumable side, as we mentioned.
Charles Weston
Thank you.
Operator
The next question comes from Oliver Metzger from ODDO BHF. Please go ahead.
Oliver Metzger
Good afternoon. Thanks a lot for taking my question.
It's about the full-year guidance. Q1 experienced still some headwinds, and also had from the Q1 last year, let's say, a higher comparable base for the consumable side.
Momentum from the consumables over the next quarters should not meaningfully deteriorate just from the space effect or remain similar. As you said, equipment demand is seen to improve, and also we observe now a gradual improvement or recovery of LPS.
Would you describe Q1 as a trough with regards to growth rates for the current year, if not any unforeseen headwinds pop up?
Florian Funck
I would not do that. It is a solid start into the year.
It is very much in the midpoint of our guidance, and I think we have, especially when issuing the guidance, have also communicated about the drivers of the guidance, what might lead to the lower end, what might especially lead to the higher end. We said that the lower end would be more as a kind of not so much expected scenario, and the higher end would require quite healthy dynamics also in the equipment area to take place, whereas the midpoints would see an equipment business rather on prior-year level.
I think we have seen now in Q1 a healthy start in the consumables business. We are going to see, at least this is the current point of view, that H1 from the equipment side would be at least on prior-year level, and with that, I feel very comfortable with the overall guidance, and to frame Q1 as a trough, I would be cautious.
Oliver Metzger
Okay. Thank you.
Operator
The next question comes from Odysseas Manesiotis from BNP Paribas. Please go ahead.
Odysseas Manesiotis
Hi. Thanks for taking my questions.
I also had a question on phasing throughout the year. Is it fair to assume Q2 could be the strongest growth quarter given your easier comps here?
I remember you had some fluid management-related US Customs delays that made Q2 '25 a bit weaker. Could you confirm whether that's a sensible way to think about it?
Florian Funck
Thank you, Odysseas. If you if you look at at absolute numbers, you've seen that the year or that Q2 in the year '25 was somehow standing out.
It was above Q1 in absolute terms, and it was above Q3. It's true that the tariffs were ramping up with the implementation of the tariffs middle of April.
Q2 took some time, and of course, the tariff effects are more pronounced in H2 '25 and and not so much in Q2. Nevertheless, I would I would say that that Q2 is a a a not too low comp if we if we look forward into Q2.
As I said, was higher in absolute terms than Q1 and Q3.
Operator
The next question comes from Thibault Boutherin from Morgan Stanley. Please go ahead.
Thibault Boutherin
Thank you. I just want to come back on the comments on equipment and I guess the sustainability that you expect from this.
I guess first of all, to what extent your conviction of improvement in Q2 is coming from the order books versus just expectations and discussions? Sort of what lead time do you have on the order book in equipment giving you that confidence?
Then related to that, are you confident this is the beginning of a recovery cycle that we've been waiting for for some time, or could we still be in a period of fluctuations where we could see equipment order and equipment sales being a bit more volatile for the next few quarters? Thank you.
Florian Funck
Thank you. Let me quickly start on the visibility on equipment for Q2.
Making this statements requires support by order book, and this is exactly what we're seeing. We're feeling quite confident looking at the order book.
Of course, there might always be late adjustments from the customers indicating they want to have certain orders in June, and then maybe, I don't know what happened at their site, requesting something in July. The general volume is clearly in the order book already for Q2.
René Fáber
Absolutely right, Florian. What I would add to that is that, I I'm not sure it's like a, as as we expect at least flat full-year sales equipment, I I would rather call it still a transition year.
We, however, are quite positive with the outlook, that that the orders in the year, full year on equipment will be above above the in H1 above the H1 last year, and also for the full year above of above 2025. As I as I as I mentioned before, funnel is there, the the discussions we have with customers indicate that that positive development, but it's still still a, yeah, positive, but transition year regarding that.
Thibault Boutherin
Thank you.
Operator
The next question comes from James Vane-Tempest from Jefferies. Please go ahead.
James Vane-Tempest
Yes, hi. Thanks for taking my questions.
I've just got a question on underlying profitability, just to understand the construct. Because if margins are basically flat year-over-year, the other operating income seems to have had a 2.5 percentage benefit because, I guess, Q1 last year was -12 and that's moved to +10.
I'm just wondering if you can help us understand what's contributing to that level and if that's sustainable. If then that actually has had such a big benefit in a swing, it looks as if the underlying margins have gone from over 31 to sort of less than 29, of which the largest driver seems to be at the gross margin level, which is down 2 2.7%, I think it is.
The second part to the question then is you've clearly talked about mix, but can you also help us understand the inventory writedowns which happened last year, and when that's exposed to start to improve over the coming years? If that math sort of makes sense, what's happening in the underlying profitability?
Thank you.
Florian Funck
Thank you, James, for your question. Let me start with that.
Yes, of course, well spotted when we're looking at gross margin. The one really big driver in gross margin is FX.
As we have a rolling forward hedging strategy on FX, but the positive hedging effects on FX on that margin are rolling in other income. There is a kind of mismatch if you're looking at that, and therefore it is in the consequence clear that you observe a healthy other income margin and a pressure on gross margin.
Now regarding inventory, what we have been talking was more a kind of general statements to give you a feeling for possible support for further margin increase, rather than giving you a concrete number that you can bring on a timeline. Please accept my apologies for not going deeper on this for your modeling.
James Vane-Tempest
Thank you. Just so I understand, what you're saying is the swing is just due to that sort of mismatch in FX.
Should we really be considering gross margins, looking at what your gross profit is with an adjustment for what we see in the other operating? Is that correct?
If we've seen this big swing, is that the sort of the level of anticipation we should have for this year? Because I noticed that the same number in Q4, or is it the type of thing which will then roll off in the second half of the year?
The reason I'm asking is because there is a sort of material to the overall margin overall, it would just help us sort of build the complete corporate picture.
Florian Funck
James, we are guiding on underlying EBITDA margin, not on gross profit margin. Therefore, we've taken appropriate measures to secure that level of profitability.
There is that FX swing, and there is another point that we also communicated in this call here, that is around the mix effect, that of course also had a certain slight drag besides tariffs on the gross profit margin. Please always bear in mind Q1 last year was free of any tariffs, Liberation Day tariffs.
Please also bear in mind that we have that kind of mix effects within BPS consumables.
James Vane-Tempest
That's great. Thanks for taking the follow-up.
Florian Funck
Thank you.
Operator
The next question comes from Naresh Chouhan from Intron Health. Please go ahead.
Naresh Chouhan
Hi there. Thanks for taking my questions.
A couple of bigger-picture ones, please. We calculate the underlying demand for mammalian biologics is low double digit, obviously which you returned to last quarter.
I heard your comments just now that we should caution that we may not see that this year. If the underlying demand is low double digits, can you help us understand the delta between your sales growth?
Is this a share issue? Is it yields?
What's happening? Why are you not growing at the rate of demand?
Secondly, as yields continue to improve, this is a more of a question around equipment. As yields continue to improve, are you seeing customers increasingly shifting to smaller batch bioreactors compared to the last few years, and therefore could it be that in equipment, that your share can improve?
Thank you.
René Fáber
Yeah. Thanks for that question.
I agree with what you said on the demand. However, this is something you need to consider over longer period of time.
Looking at a year, there might be fluctuations, but overall, this is what we see and expect. When we talk about market fundamentals and growth, we see that and expect that the biologics demand will grow and continue grow.
Low double digit is fair assumption. At the same time, improvements happen that has also impact, as you indicated, on then what consumables and equipment are used.
Yes, we have seen, but it's now for more than a decade that this yield or efficiency improvement leads to more and more smaller-volume processes, more and more single-use adoption. If you listen to our Capital Markets Day, this is also the expectation we have, and what we do and drive as an innovation in industry is further improvement of this efficiency, so that even more of especially commercial drugs will be manufactured in that smaller, more flexible single-use equipment and facilities, which of course will positively impact and drive our market position and the growth of the business.
Naresh Chouhan
Can I just ask a follow-up? Should we then assume on the basis of that your equipment sales should hold up pretty well, but consumables will grow slower than underlying demand over the kind of short to medium term?
René Fáber
No.
Naresh Chouhan
Okay. Thank you.
Operator
The next question comes from Falko Friedrichs from Deutsche Bank. Please go ahead.
Falko Friedrichs
Thank you. I have one question, please.
Is it fair to assume that the group adjusted EBITDA margin in Q2 is likely still below the full-year guidance range, just like it was in Q1, given the incremental tariff headwind and more equipment in the mix?
Florian Funck
Could be. Depends also on the other components of mix, Falko.
Falko Friedrichs
Okay. Fair enough.
Thank you. Then
Operator
the next question comes from Theodora Beadle from Goldman Sachs. Please go ahead.
Theodora Rowe Beadle
Hi, thanks for taking my question. Can you talk to how you're managing the current geopolitical risks and energy price increases, and what are the key mitigating strategies that you have in place?
Thank you.
Florian Funck
Thank you very much. When we are talking about the Iran crisis and energy prices, first of all, it has to be noted that Sartorius is not to be considered as a kind of energy-intensive company.
If we purely talk about electricity, it is a very low single-digit percentage of cost of goods sold. In recent years, we have also invested in expanding renewable energy capacity at our sites worldwide to become more independent, of course, over time from fossil-based energy.
We are not using short-term hedging instruments, but what we're using are our longer-term rolling contracts. Even if we see on the spot markets hikes in gas or electricity, this should not have any larger impact on our P&L in '26 and in '27.
On the other hand side, there might be indirect or second-round effects from rising energy and/or gas prices on costs, for example higher freight costs or oil-based components in raw materials, plastic for example. This is of course somewhat more relevant, and we are watching the supply and sourcing situation very carefully.
We have a task force on top of that. This might lead already in the year '26 to an increase of our cost base.
On the other hand side, most of our supply contracts are longer-term, and even if we have higher price levels, they will also be mitigated by internal moving average prices based on inventory in place. Furthermore, currently we have no significant component shortages that have been identified by the task force that I was mentioning.
Of course, even if there were some cost effects, and if I had to put a risk number, it would be, I don't know, round about €10 million for the year '26, we would then act and implement countermeasures, including price increases or freight surcharges, and this is all currently evaluated. Of course, if the conflict is prolonged and we're seeing persistently higher oil prices, that of course could have an impact on costs in 2027, but this is now too early to tell.
I can tell you that we have overall the instruments in place to fare our way also in an inflationary environment.
Operator
The next question comes from Charles Weston from RBC Europe. Please go ahead.
Charles Weston
Hello, thanks for taking the follow-up. I just have one, please, on the comps.
I know the question's been asked before, but you've talked about there being tougher comps in 2026 on the consumable side, but I thought that 2025 was effectively described as a more normal situation in absolute revenue terms. If there was additional sort of restocking by customers in '25 making the comps tougher, perhaps you could just discuss that.
If not, and it was more normal, then why would 2026 consumable growth be lower because of tough comps? Thank you.
Florian Funck
I'm not sure I really got the question, because what we've seen in prior year in consumables was a growth in consumables that was definitely above average market in a still transitioning year. Based on that, I would simply say it is not fair to assume that these high kind of growth rates will persist in the year '26, and that we will see base effects.
When I was talking about comps, it was based on the question regarding Q2, where I just said that Q2 stood out in absolute volume against Q1 and Q3.
Charles Weston
Okay. Thank you.
Operator
The next question comes from Delphine Le Louët from Bernstein. Please go ahead.
Delphine Le Louët
Yes, hello. Morning, everybody.
Just to be back into the mix effect, and specifically at BPS, René, can you clarify a bit more the impact in between the volume and the price, if any, or in between the consumable or the service versus the rest of the line when it comes to the equipment? Can we have a bit more granularity here, please, for us to really understand?
René Fáber
Thank you very much for the question. We've seen that in the quarter, we see this more as a quarter effect, nothing to be continued and move forward.
It's really a short-term make shift to a certain, yeah, parts of the portfolio, nothing structural.
Delphine Le Louët
Okay. There is nothing on the price?
Nothing specific? Just regular price increase?
René Fáber
No. There's nothing to do with the price as such.
No. Yeah.
Operator
Ladies and gentlemen, this was the last question. I would now like to turn the conference back over to Petra Müller, Head of Investor Relations, for any closing remarks.
Petra Müller
Thank you, operator. This concludes today's call.
Please reach out to the investor relations team in case of any open questions. We thank you for joining today's call, wish you a pleasant rest of the day, and see you next time.
Operator, you may now disconnect.
Florian Funck
Thank you.
Operator
Ladies and gentlemen, the conference is now concluded, and you may disconnect. Thank you for joining and have a pleasant day.
Goodbye.
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