Jounce Therapeutics, Inc.
NASDAQ Global SelectRecent
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- Jounce Therapeutics, Inc., a clinical-stage immunotherapy company focused on developing novel cancer therapies, advances monoclonal antibodies targeting immune checkpoints and tumor-associated macrophages, including vopratelimab (JTX-2011), a Phase II ICOS agonist for solid tumors; JTX-8064, a LILRB2 antagonist in Phase I INNATE trials as monotherapy and combined with pimivalimab, Jounce's anti-PD-1 antibody; pimivalimab for combination regimens; and preclinical candidates JTX-1484 and JTX-2134 designed to reduce myeloid suppression and activate T and NK cells. Founded in 2012 and headquartered in Cambridge, Massachusetts, the company primarily serves oncology markets through biomarker-driven approaches for advanced solid tumors such as non-small cell lung cancer and platinum-resistant ovarian cancer. In May 2023, Jounce became a subsidiary of Concentra Biosciences, LLC following a $1.85 per share cash acquisition plus contingent value rights tied to program dispositions, accompanied by an 84% workforce reduction and termination of a prior Redx Pharma merger; its website now redirects to Concentra, which continues integrating Jounce's pipeline amid ongoing 2025 buyout activities.
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Gilead buys out rights to cancer therapy from Jounce for $67 mln
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Jounce Therapeutics to Present Multiple Posters at the Society for Immunotherapy of Cancer's (SITC) 37th Annual Meeting and the European Society of Medical Oncology Immuno-Oncology (ESMO-IO) Annual Congress
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