Janus Henderson Global Select Fund N Shares (JSLNX) is an open-end mutual fund that seeks long-term growth of capital in a global equity portfolio of 40 to 70 common stocks selected for their underestimated free-cash-flow growth potential across market caps, styles, growth, and value criteria; it invests primarily in large-cap blend equities domiciled in the United States with flexibility for domestic and foreign issuers, benchmark-agnostically emphasizing high-quality companies benefiting from secular trends in sectors such as technology, financial services, industrials, consumer cyclical, and communication services. The fund, launched on August 4, 2017, with Julian McManus as lead manager since January 2018 and Christopher O'Malley joining in January 2024, maintains total net assets of approximately $3.01 billion and a net expense ratio of 0.68%, requiring a minimum initial investment of $1 million and available for sale in the United States. Janus Henderson Investors, the fund's adviser formed by the 2017 merger of Janus Capital (founded 1969 in Denver, Colorado) and Henderson Global Investors (roots in 1934 in London), operates from headquarters in Denver with global offices including London. Recent strategic developments at Janus Henderson include the August 2024 announcement to acquire a majority stake in Victory Park Capital, a global private credit manager, complementing its $36.3 billion securitized credit assets under management and expanding private markets capabilities expected to close in Q4 2024; a multifaceted April 2025 partnership with Guardian Life Insurance to manage $45 billion in investment-grade fixed income, commit up to $400 million in seed capital for fixed income innovations, and co-develop multi-asset portfolios; and earlier 2024 moves like partnering with NBK Wealth for emerging markets private capital. The fund's portfolio features top holdings such as Taiwan Semiconductor (5.92%), Microsoft (5.30%), BAE Systems (5.11%), NVIDIA (4.60%), and Ferguson Enterprises (4.40%), with 56% U.S. stocks, 41% non-U.S. stocks, and 3% cash, targeting institutional investors seeking risk-adjusted returns through disciplined stock selection and global diversification.