LakeShore Biopharma Co., Ltd
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- LakeShore Biopharma Co., Ltd (NASDAQ: LSB) is a global biopharmaceutical company dedicated to the discovery, development, manufacturing, and commercialization of innovative vaccines and therapeutic biologics targeting infectious diseases and cancer; its proprietary PIKA immunomodulating technology platform drives a pipeline including the marketed YSJA rabies vaccine, the first aluminum-free lyophilized rabies vaccine in China; PIKA rabies vaccine in Phase I/III trials; PIKA YS-HBV-001 and PIKA YS-HBV-002 for hepatitis B prevention and chronic infection treatment in Phase I and preclinical stages, respectively; PIKA YS-ON-001 immuno-oncology candidate in Phase I for pancreatic and hepatocellular cancers; and preclinical candidates for influenza, shingles, coronavirus, and other viral infections. Founded in 1994 and headquartered in Beijing, China, at Building No. 2, 38 Yongda Road, Daxing Biomedical Industry Park, the company operates primarily in China, Singapore, the Philippines, the United States, and the United Arab Emirates, serving markets for preventive vaccines and immunotherapeutics with approximately 573 employees. Formerly known as YS Biopharma Co., Ltd., it changed its name to LakeShore Biopharma in May 2024 to better align with its global positioning; recent developments include a US$15 million private placement financing in July 2025 with an institutional investor issuing ordinary shares and warrants; entry into a definitive agreement in November 2025 for a going-private transaction; receipt of preliminary non-binding acquisition proposals in August 2025, including a revised one from a consortium; Philippine FDA approval in April 2024 for Phase I trials of YS-HBV-002; and transition to OTC markets following Nasdaq delisting.
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