- Business
- Adocia SA (ADOC.PA) is a clinical-stage biotechnology company that develops innovative formulations of approved therapeutic proteins and peptides, as well as novel cell therapy approaches, primarily for the treatment of diabetes and obesity; its proprietary platforms include BioChaperone for new-generation insulins and hormone combinations, AdoShell for immunoprotective islet cell transplantation, AdOral for oral peptide delivery, and AdoGel for long-acting drug delivery. Key products in its diversified pipeline encompass BioChaperone Lispro, an ultra-rapid prandial insulin formulation licensed to Tonghua Dongbao for China and select Asian markets and ready for Phase 3 trials in the US and Europe upon partnership; BioChaperone Combo, a fixed-ratio co-formulation of insulin glargine and lispro for type 2 diabetes; M1Pram and BioChaperone LisPram, pramlintide-insulin combinations with Sanofi for glycemic control and weight management in obese diabetic patients; AdoShell Islets, a retrievable hydrogel implant for type 1 diabetes cell therapy; AdOral Sema, an oral semaglutide; and AdoGel Sema, a steady-release injectable semaglutide hydrogel, with additional assets like BioChaperone GLP-1 Amylin in development. Founded in 2005 by the Soula family and headquartered in Lyon, France, the company targets patients with type 1 and type 2 diabetes and obesity globally through partnerships, with operations centered in Europe and licensing in Asia. Recent developments include a €9.7 million private placement in February 2025 led by Armistice Capital and existing shareholders, extending cash runway to Q2 2026; a US$10 million milestone from Tonghua Dongbao in 2025 following positive Phase 3 topline results for ultra-rapid BioChaperone Lispro (THDB0206) in type 1 diabetes; €10 million upfront from Sanofi for exclusive negotiation rights on M1Pram, with ongoing partnership discussions; a new patent filing in November 2025 for the AdoXLong long-acting peptides platform alongside BioChaperone updates; and oral presentations on AdoShell and BioChaperone at EASD, ESB, and PODD 2025 meetings.