Physiomics Plc

Physiomics Plc

LLSE:PYC
0.48
GBX
0.00
(0.00%)
129.16MMarket Cap
Mar 11Next Earn
Physiomics Plc
LSE:PYC
(London Stock Exchange)

Recent

price

0.48

P/E

ratio

- -

div

yld

- -

ROIC.AI

2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
TTM
GBP
0.02
0.01
0.01
0.02
0.02
0.01
0.01
- -
0.01
0.01
0.01
0.01
0.01
0.01
- -
- -
- -
Revenue per Share
-0.04
-0.06
-0.05
-0.03
-0.03
-0.02
-0.01
-0.01
- -
- -
- -
- -
- -
- -
- -
- -
- -
Basic EPS, GAAP
-0.05
-0.06
-0.05
-0.03
-0.02
-0.02
-0.01
-0.01
- -
- -
- -
- -
- -
- -
- -
- -
- -
Free Cash Flow per Basic Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Dividend per Share
0.08
0.07
0.05
0.02
0.01
0.01
0.01
0.01
0.01
0.01
0.01
0.01
0.01
0.01
- -
- -
- -
Book Value per Share
0.08
0.06
0.05
0.02
0.01
0.01
0.01
0.01
0.01
0.01
0.01
0.01
0.01
0.01
- -
- -
- -
Tangible Book Value per Share
9
10
12
15
16
21
29
51
59
72
74
97
97
97
135
238
303
Basic Weighted Avg Shares
- -
- -
- -
- -
- -
- -
- -
- -
- -
1
1
1
1
1
1
1
- -
Sales/Revenue/Turnover
-256.86
-1,300.58
-427.12
-228.48
-173.67
-176.13
-137.52
-222.72
-60.8
-27.99
-16.82
-47.99
-43.25
-96.05
-123.48
-58.39
- -
Operating Margin (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Depreciation Expense
- -
-1
-1
-1
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
-1
- -
- -
Net Income, GAAP
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Effective Tax Rate (%)
-240.52
-1,208.23
-398.78
-208.57
-158.87
-151.88
-127.46
-182.35
-42.81
-14.47
-8.06
-30.73
-30.49
-79.9
-112.17
-52.97
- -
Profit Margin (%)
1
1
1
- -
- -
- -
- -
- -
1
1
1
1
1
1
- -
1
- -
Working Capital
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
LT Debt
1
1
1
- -
- -
- -
- -
- -
1
1
1
1
1
1
- -
1
- -
Total Equity
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Capital (%)
- -
-83.57
-72.42
-101.09
-216.98
-154.79
-142.97
-150.46
-36.01
-16.03
-6.7
-17.4
-23.65
-63.36
-149.67
-85.21
- -
Return on Common Equity (%)

Capital Structure

GBP

•

in mil. unless spec.
Dec'25
Jun'25
Dec'26
ST Debt
- -
- -
- -
LT Borrowings
- -
- -
- -
LT Finance Leases
- -
- -
- -
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
303
303
453
Market Capitalization
2
1
1

Working Capital

GBP

•

in mil. unless spec.
Dec'25
Jun'25
Dec'26
Total Current Assets
1
1
1
Cash, Cash Equivalents & STI
- -
- -
- -
Accounts Receivable, Net
- -
- -
- -
Inventories
- -
- -
- -
Total Current Liabilities
- -
- -
- -
Payables & Accruals
- -
- -
- -
ST Debt
- -
- -
- -
Deferred Revenue
- -
- -
- -

Growth Rates

GBP

•

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
26.3%
4.99%
144.99%
Free Cash Flow
58.08%
131.26%
-2.72%
Net Income, GAAP
21.28%
67.33%
-31.85%
Sales/Revenue/Turnover
18.74%
2.66%
44.32%
Total Cash Common Dividend
- -
- -
- -

Semi-annual Revenue

GBP

•

in mil. unless spec.

Year

H1
H2
FY
2024
- -
- -
1
2025
- -
- -
1
2026
- -
- -
- -

Semi-annual Earnings Per Share

GBP

•

in mil. unless spec.

Year

H1
H2
FY
2024
- -
- -
- -
2025
- -
- -
- -
2026
- -
- -
- -

Semi-annual Dividends Per Share

GBP

•

in mil. unless spec.

Year

H1
H2
FY
2024
- -
- -
- -
2025
- -
- -
- -
2026
- -
- -
- -
Business
Physiomics Plc is a United Kingdom-based company specializing in providing outsourced quantitative pharmacology, computational biology, mathematical modeling, biostatistics, and data science consultancy services primarily to pharmaceutical and biotechnology companies. Its core offerings include model-informed drug development (MIDD), predictive quantitative systems pharmacology (QSP) through its proprietary Virtual Tumour software, simulation and data analysis services across oncology research and drug development stages, biostatistics, bioinformatics, and technology for personalized medicine. The Virtual Tumour software is a semi-mechanistic model that integrates biological processes such as the cell cycle, DNA damage and repair, and immune response, supporting the design and optimization of preclinical and clinical studies. Founded in 2001 and headquartered in Oxfordshire, England, Physiomics serves clients mainly in the UK, European Union, Switzerland, and the United States. The company leverages industry-standard tools such as NONMEM and MATLAB alongside its proprietary platforms and bespoke R programming models to deliver tailored solutions across drug discovery, preclinical, and clinical phases. It operates within the biotechnology and pharmaceutical sectors, targeting drug developers focused on oncology, personalized medicine, and quantitative pharmacology. Recent major changes include the announcement of the CEO Peter Sargent's planned departure in May 2026 while the non-executive chair, Jim Millen, will resume executive chair responsibilities to ensure business continuity. The company has reported strong business momentum with record contracted projects and revenue growth initiatives, including a new biometrics service line that has already generated revenue. Physiomics also announced the relocation of its registered office to Milton Park Innovation Centre, Oxfordshire, effective October 2025. Furthermore, it secured new contracts in late 2025 to accelerate promising drug programs, demonstrating ongoing commercial progress and strategic growth in model-informed drug development services. Physiomics continues to expand its capabilities through advanced modeling, simulation, AI, and machine learning applications to support its pharmaceutical clients worldwide, maintaining a focus on integrating computational predictions with experimental data to de-risk drug development and improve therapeutic outcomes. The company maintains a lean workforce of approximately 6 to 10 employees and is publicly traded on the London Stock Exchange AIM market under the ticker PYC.L.