Operator
Please note this conference is being recorded. I now hand over the call to Mr.
Ganesh Nayak, Director at Zydus Lifesciences. Thank you, and over to you, sir.
Ganesh Nayak
Good evening, ladies and gentlemen. It's my pleasure to welcome you all to our post-results teleconference for the first quarter ended June 30th, 2026.
For today's call, we have with us Dr. Sharvil Patel, Managing Director; Mr.
Tushar Shroff, Chief Financial Officer; Mr. Arvind Bothra, Head of Investor Relations; and Mr.
Alok Garg from the Managing Director's office. To begin with, let me talk about the key developments during the quarter.
I'm happy to report that we commenced FY '27 with strong double-digit growth, building on the formidable base of FY '26. This performance reflects the sustained momentum across all our key businesses, each of which contributed meaningfully to the overall performance during the quarter.
With this, first of all, let me walk you through the financial performance for the quarter under review. We registered consolidated revenues of ₹80.2 billion, up 22% on a year-on-year basis.
On the operating profitability front as well, our performance was robust with an EBITDA margin of 24.1%. Consequently, EBITDA for the quarter stood at ₹19.3 billion, while net profit for the quarter stood at ₹9.4 billion.
Our net debt to EBITDA ratio stood at 0.7 times as on the 30th of June 2026. Now let me take you through the operating highlights for the first quarter of FY '27 for our key business segments.
In the pharmaceutical space in India, our branded formulations business sustained market outperformance with a strong 20% year-on-year growth during the quarter. This business has, in fact, outperformed the market growth consistently over the last three financial years.
Growth during the quarter was broad-based as we grew faster than the market in super specialty, chronic, as well as acute segments. In terms of therapy performance, the business grew faster than the market in cardiology, diabetology, gynecology, anti-infectives, pain management, and in the super specialty areas of oncology and nephrology.
Our ranking improved in three key therapies of cardiology, diabetology, and pain management, while on the super specialty front, we continued to retain leadership position in the oncology therapy. Our large innovative brands, led by Lipaglyn, continued to strengthen their market standing and improve their rankings quarter after quarter, underscoring the impact of our innovation on improved patient outcomes.
Contribution of chronic and sub-chronic portfolio has increased consistently over the last several years and stood at 54.2% as per AWACS MAT June 2026, an improvement of 360 basis points over the last four years. International markets formulations business has delivered strong growth during the last several quarters and has established itself as a formidable growth pillar for the company.
The business sustained the growth momentum during the quarter and posted revenues of ₹9.7 billion with a year-on-year growth of 34%. The growth was led by strong demand-driven performance across markets and supported by focused execution.
North America business, comprising of the US and Canada, exhibited resilience with revenues of ₹31 billion during the quarter, up 5% quarter-on-quarter. The base US business continued to gain share driven by sustained volume expansion, supplemented by new product launches.
On the US generics front, we filed 5 ANDAs, received 9 approvals, including 4 tentative approvals, and launched 11 new products during the quarter. Our US specialty business achieved two important milestones during the quarter.
First, we launched Neofinco injection, which is ranibizumab, our first biosimilar in the US market, marking a meaningful expansion of our specialty capabilities and laying the foundation for future participation in the growing biosimilars segment. Second, we completed the acquisition of Assertio Holdings, significantly strengthening our commercial capabilities, portfolio breadth, and market access in the US specialty space.
These milestones underscore our continued focus on building a robust specialty platform in the US and advancing our transition towards a more differentiated, innovation-led business model. In Canada, we received 2 ANDS approvals and launched 2 new products during the quarter.
Our Consumer Wellness business recorded revenues of ₹14.3 billion, up 67% year-on-year. With this, the international business, including the Comfort Click portfolio, delivered a like-to-like growth of 25%, while the domestic business grew 5% year-on-year.
Within the domestic portfolio, skin and hair care, and food and nutrition continued their strong momentum, delivering growths of 35% and 16%, respectively. Seasonal brands, however, degrew primarily due to the softer summer season.
In the medical devices space, the business registered revenues of ₹2.8 billion during the quarter. We are investing in enhancing our capabilities in the focused therapies, which offer long-term growth potential to create differentiated value.
On the operations front, our injectable manufacturing facility at Zydus Biotech Park recently received an Establishment Inspection Report (EIR) with a Voluntary Action Indicated (VAI) classification following a GMP surveillance inspection conducted in April and May 2026. During the quarter, we entered into a joint venture agreement with Sunshine Healthcare to establish a pharmaceutical manufacturing facility in Sri Lanka to strengthen local production and reduce import dependence for the country.
Now this concludes the business review. I would now request Dr.
Sharvil Patel to take you through the key drivers across businesses as well as initiatives in our innovation program. Thank you.
Sharvil Patel
Thank you, Mr. Nayak, and good evening, ladies and gentlemen.
It's a pleasure to have you all here today on our call. FY '27 is off to a great start with a strong performance across the key businesses.
More importantly, we continue to advance our transformation into an innovation-led organization. The share of our branded portfolio in the total revenues has steadily increased over the last several quarters.
It accounted for over 55% of our total revenue in the first quarter of this year. As our branded business continues to gain scale across markets, we expect their share to exceed two-thirds of our overall revenue over the medium term.
I'm confident that the strategic choices that we have made over the last several years will build strong growth pillars for us in the long term. With our innovation efforts translating into commercial opportunities, a growing branded portfolio, and disciplined execution across businesses, we are well positioned for our next phase of growth.
On the pharmaceuticals front, our strategy for India formulations business is working favorably. The branded business delivered a formidable 20% growth during the quarter.
In fact, the business has been consistently outperforming the market growth over the last several quarters. A key driver of this outperformance is our chronic portfolio.
These therapies continue to gain share and significantly aid to our overall growth momentum. This is further supported by the strong uptake of our innovation and differentiated portfolios.
In addition, our brand building initiatives and a stronger execution focus are delivering clear results. We remain fully confident in our ability to outpace the industry growth and grow sustainably.
Our international market formulations business continued to deliver strong growth and has emerged as a formidable growth pillar for the company. While our therapy-led strategy continues to drive momentum in the emerging markets, portfolio expansion and deeper market penetration in Europe are supporting this sustained growth momentum across the business.
We have steadily strengthened our position in the US generics market through a diversified portfolio, a stronger execution, and a resilient supply chain. This is reflected in sustained prescription group market share gains and improved market rankings, reinforcing our position as a trusted generics player in the US.
I'm pleased to report that our branded business in the US now contributes 10% of our revenue in the US. We expect the share of this segment in the US to continue to increase as our specialty and innovation-led business gains scale.
The growth drivers are firmly in place, vis-a-vis orphan and rare disease franchise, a growing portfolio of 505(b)(2) products, the recent acquisition of ROLVEDON, and an NDA submission to the US FDA of saroglitazar, our first internally developed innovation in the US. Collectively, these businesses position us for a sustained shift towards a more differentiated and specialty-driven US portfolio.
In the Consumer Wellness business, we continue to build a future-ready portfolio through innovation, disciplined execution, and data-driven decision-making. Our investments in analytics and digital capabilities are enabling sharper consumer insights, improving resource allocation, and sustainable profit growth.
In the MedTech, we continue to strengthen our presence across the orthopedics, cardiology, and nephrology while building a scalable platform for long-term growth. Leveraging Amplitude's orthopedic portfolio and the proprietary Andy robotic surgical system, we're expanding access to advanced solutions.
At the same time, we're broadening our cardiology offerings and establishing a high-end dialyzer membrane facility to address growing global demand in nephrology. With this, let me share some material developments on the innovation effort during the quarter.
On the NCE research front, the US FDA granted priority review to our New Drug Application of Saroglitazar Magnesium for the treatment of primary biliary cholangitis. Recently, we received also a regulatory approval in India to initiate a Phase III clinical trial of desidustat in patients with sickle cell disease.
The study will be conducted in collaboration with ICMR. Desidustat represents a potentially first-in-class therapeutic opportunity for the treatment of sickle cell disease.
On the biotech R&D space, we initiated a Phase III clinical trials in India for our second ADC of biosimilar. This development further strengthens our deep and differentiated biologics pipeline and underscores our capability in developing advanced biologics.
It further enhances the long-term growth potential of our biologics franchise. On the vaccines R&D, we completed our Phase II trial of the bivalent typhoid conjugate vaccine and also initiated a Phase I trial of our chikungunya vaccine in India.
On the global development front, we submitted our dossier of the MR vaccine to WHO. The dossier has been accepted for review.
Thank you, and now we can start with the Q&A session. Over to the coordinator for the question and answers.
Operator
Thank you, sir. We will now open the call for Q&A session.
We will wait for few minutes until the queue assembles. We request participants to restrict to two questions and then return to the queue for more questions.
Please raise your hand from the participant tab on the screen to ask the question. The first question is from Kunal Dhamesha.
Kunal Dhamesha
Hi, good afternoon. This is Kunal from Macquarie.
Thank you for the opportunity, and congratulations on strong set of numbers. Dr.
Sharvil, with quarter one suggesting strong top-line growth, would we be kind of looking at a much higher growth than what we have guided for FY '27, which is currently double-digit is what we have said? That's the first question.
Sharvil Patel
Thank you for the wishes, and I think we continue to stay with our guidelines that we will deliver strong double-digit growth for the year starting with the first quarter. I think our India business is poised to deliver significantly good traction better than market at least by 300 to 500 basis points.
We see a mid-teens growth continuing for that business. Is our international markets, and US being around single-digit growth.
Looking at that, we will still see good growth for the coming year in revenue.
Kunal Dhamesha
Sure. For the India business, I think last time we shared the share of the progressive brand, I believe, that with a strong growth.
Has that gone up meaningfully in this quarter, and should we expect that momentum of progressive brands to kind of continue at that level?
Sharvil Patel
Yes, I think we have seen more than expected exceptional strong growth on our innovation portfolio, which has beaten our current expectations. Also, on our value-based biosimilars, we have seen a very significant uptake on all brands.
That has seen a very significant uptake also. I think both of them have significantly aided to this momentum, and at the same time, which has also led to an improvement in our chronic basket and our growth booster brand.
I would say it's all-round performance across, but of better than expected on the innovation and biosimilars, and also the scaling up of vaccines.
Kunal Dhamesha
Sure. The last question that I have is on the overall, some of these new growth drivers, right?
In the medium term, we suggested that the branded pieces will become more than two-thirds of the revenue, right? Would you say most of this new drivers would aid to our profitability over medium term?
Sharvil Patel
Yes, I think if I break down into businesses, India and EM, I agree that with the improvement in our portfolio of branded as well as chronic, we'll see better profitability. On the US, I would say the only scale-up that we need to do is Saro, which will require investments.
If you take our other portfolio, which is our Sentynl, that is already broken even and profitable and will continue to aid to profitability. We are seeing our portfolio on the 505(b)(2) also becoming profitable from now and growing.
As I said, today it's only 10% of our business, and probably by end of the year, it'll cross 15% or more, and we can only see that increasing meaningfully.
Kunal Dhamesha
Sure. Thank you, and all the best.
Operator
Thank you. The next question is from Neha Manpuria.
Thanks for taking my question. My first question is on the increase in the operating cost that we have seen in the current year, given that we'll have the full impact of Assertio as well as Saro spend.
How should we think about both the employee cost as well as the SG&A cost? When should we start expecting the incremental Saro cost to flow through?
Just an update on our margin guidance. Are we still maintaining the 24%+ margin guidance that we had indicated?
Sharvil Patel
Saro, there is already certain costs that have started, but we would see a increase in the second half of the year. Owing to that meaningful increase that we'll see in the second half, we are still guiding towards the 24% kind of margin.
Tushar Shroff
Our current run rate of about 1,900 to 2,000 crores, I think that kind of a run rate I think we should assume as a part of the other expenses excluding R&D on a quarterly basis.
This is despite us increasing the spend on Saro?
Tushar Shroff
It's all-inclusive.
Okay. The increase that we have seen quarter-on-quarter so far is essentially on the back of, what what would, this increase, like sir mentioned Saro is one of them, but what is the other reason for the sharp increase that we have seen in costs, quarter-on-quarter?
Tushar Shroff
It's all acquisition-driven, the impact that we see on increase in the other expenses. Largely, I would say that about 80% is increase in the cost is driven by acquisitions that we had in last one year.
That I understand, sir. Year-on-year, I understand, but even if I look at this number quarter-on-quarter, it seems like a fairly steep increase.
Sharvil Patel
Zymergen, Assertio, and the freight expenses.
Okay. Understood.
My second question is on the CapEx. We see a pretty sharp increase in CapEx this quarter as well.
If you could give us some color in terms of where we are spending in terms of CapEx and what the guidance for the full year would be? At the CapEx
Sharvil Patel
from the CapEx point of view, I think a meaningful part of it, obviously, is setting up of the facilities, SEZ 3, which has come in right now; the completion of the expansion that we have done in our existing facilities for higher capacity, including Moraiya, Goa, Baddi, and unit and then unit 2, unit 3 and SEZ. We are also building a new higher bigger R&D center for formulation development, which has happened.
There's one-off investment in Wellness for a larger land acquisition for future facility, which is a little exceptionally for one-time kind of investment. Then it's a new CAR-T facility that we built for biologics, a new vaccines DS facility.
There are multiple things that have led to this increase, including some investment that continues in Zymergen also. It's a whole host of many things, it's not a one particular thing that is a large item other than the Wellness land acquisition, but multiple investments in increasing scale and capacity in existing and new capabilities.
For the full year, what would this number be in that case?
Sharvil Patel
We are right now guiding for around 1,500 to 1,600 crore CapEx.
Understood. For Saro, given that we have the PDUFA coming in the later part of this year, how should we think about the ramp-up of market share there, if you could give us some color to help us understand in terms of what the sales opportunity could be?
Sharvil Patel
On Saro, I mean our we're building for a next FY '28 launch right now, April launch. We are investing for that.
The first year of first three years, I mean first two years will be just build-up of this. We won't see any significant revenue in the first year, large.
As we move into second and third year, we would see the revenue build-up. I think it will first two years will look more from an investment point of view as to how much we're investing.
On the market point of view, obviously, if you see the recent guidance from both our both the other competitors in the current segment, they are seeing better traction than their earlier guidance, and they've upgraded some of their guidances. That is led from higher patients, bigger patient pool and more patients wanting to access this indication.
We are seeing a positive in terms of market being a being a bigger market than expected. We are only seeing some positive signs in terms of how this market formation is happening, and so quite excited with that opportunity.
Noted, sir. Any indication that you'd want to give on target market share or, let's say, peak sales that we expect from this product?
Sharvil Patel
As I always said, on our conservative side, we are looking at a $200 to $300 million range. Maybe more optimistic, we can cross the $400+ million range.
Understood. That's helpful, sir.
Thank you.
Operator
Thank you. The next question is from Sayan Mukherjee.
Hi, thanks for taking my question. On the US, sir, you mentioned, currently we have 10% of revenues coming from branded, so that would mean roughly, let's say, $130, $135 million, right, of revenues on an annual basis?
How is that? The rare disease would be $40, $50 million.
If you can throw some light, what are the other constituents and whether Assertio is a significant number in this?
Sharvil Patel
Currently in this quarter, which is 10%, we don't have any Assertio number in fully.
Our
Sharvil Patel
last year Sentynl was around $60 million, which is our rare disease business. I think Assertio will start adding from the coming quarter.
That's why we said the numbers from the analyst point of view will go up towards 15% because those numbers are still to be baked in.
Understood. You're saying rare disease is around $60 million, and the remaining $60, $70 million is 505(b)(2) products.
Would that be a right way to think about it?
Sharvil Patel
There are a cluster of 505(b)(2) products.
Okay. Sir, this Assertio acquisition, ROLVEDON sales, how should we think about the contribution this year, next year?
What's the expectation there?
Sharvil Patel
I think we've just begun, it seems to be on track. We're looking at around $15 to $20 million per quarter run rate.
We would see that from next quarter, right?
Sharvil Patel
Yes.
Understood. Sir, on the India business, we have seen a good growth here.
What's really driving, if you can give some color. Of course, you have mentioned about innovation asset.
Maybe how has semaglutide done? If you can give some color here, I'm just wondering what's the sustainable number, let's say, if I take a two, three-year horizon, how should we think about the growth for India business?
Sharvil Patel
I think I'll try and really summarize a little better. I think there are two, three things.
One is overall chronic part of our business is growing at more than 20%. If you look at even July numbers that has been reported by the AWACS, we're seeing strong traction on the chronic side of various therapies and growing very meaningfully in which helps that growth.
The second is, we are seeing a very very meaningful uptake on Saro and Desi, which is adding quite meaningfully, almost 30% to 45% kind of growth in this business. That's also adding very meaningfully and scaling up, and we see that traction continuing.
The third is our biologics have seen extremely good traction on three or four brands, which have also very, very significantly scaled after genericization also. We are seeing very strong momentum on both.
Sema is just the beginning, it is a small contributor. We are third, fourth in market share today in our own brand, but overall, we are largest as a semaglutide innovative generic that we've launched.
That also is adding to the momentum. I would say the whole differentiated pipeline and the chronic business, both helping this growth, and we see that sustaining going forward.
Understood. Sir, the 6,500 crores of revenues that was booked last year, how much would be biologics, innovation, and vaccine in that, if you can give a rough percentage?
Sharvil Patel
We have not given any break-up because it's all different divisions, which have multiple brands, both chronic and this, we don't track them separately. As I said, oncology portfolio is the fastest growing and then followed by the chronic portfolio.
Then vaccines is, obviously, a very different business, which I always said that we want to achieve the 300 to 400 kind of crore mark, and we are on track to achieve that.
Understood. Sir, if I can ask one last question, which is on the international formulation.
We have crossed $100 million of revenues this quarter, and the growth has been exceptionally strong. I would appreciate if you can give some granular color on this, either in terms of geographic segment or product segment, which is driving this.
Again, the question is around sustainability of very strong double-digit growth from, let's say, next two, three years perspective.
Sharvil Patel
I think three things. One is our four existing markets have delivered on the emerging market front, they continue to do better than last year and are growing very strongly.
The second is Europe, which used to be a little difficult business for us in terms of growth, two things have changed. Both our four old markets, the France and Spain, have significantly delivered on growth, and they continue to see a very strong traction on that.
A new market entry of UK has scaled up much faster than expected and is also becoming a very important business for us. That international part in terms of EU has started doing extremely well in terms of the revenue.
The third is we entered new geographies, and those geographies we are seeing our innovative pipeline or first generic kind of launches in many markets, which is seeing a good, healthy traction in terms of commercialization. I think all in all, all these three things are helping: core markets, the Europe doing much better, and the new markets really meaningfully scaling up.
Right, sir. Thank you very much.
Operator
Thank you. The next question is from Bino.
Sharvil Patel
Hello?
Operator
Hi, Bino. Are you able to unmute yourself and ask the question?
Sharvil Patel
I think he's unmuted, but...
Operator
Yeah. We might move to the next.
The next question is from Vamsi.
Hi, sir. Am I audible?
Sharvil Patel
Yes,
Operator
yes.
Thanks for taking my question, and congrats on the good set of numbers. My first question is in terms of the 505(b)(2) portfolio that we have.
Of the 20 assets, if I'm not wrong, close to five have been commercialized. How do you expect the overall portfolio to ramp up in terms of the launches which are scheduled for the rest of the year?
In terms of the steady-state sales, I remember in one of the calls, we have guided that some of these assets could hit a $50 million kind of mark each. How is that kind of panning out at this point of time?
Sharvil Patel
On our 505(b)(2), we have a good mix of our own products and licensed products also. We have about 19 products that we have from our in-house and own pipeline creation.
We have partner products, which are about eight, that we're working on in different areas. We have commercialized four-plus products now, as you said.
We have more products in the pipeline. I think it's a pipeline that we're trying to develop for the markets.
From the current point of view, I would say most of them are doing better than expected. I think the going out Bizra is slower than what we had expected, and we hope in the next financial year, we'll see a more bigger scale-up.
Beyond that, the other two, three products that we have launched are doing extremely well. At the same time, ROLVEDON will add meaningfully to that business going forward.
Then the biosimilars initial launch of ranibizumab and with the PFS coming next year and also further products, we will see good uptake on that. Also our specialty rare disease business on Sentynl, which has meaningfully started to do well.
All in all, I think that's doing well and is growing well.
Thank you, sir. If I just may also ask a couple of questions around the liquids portfolio.
Currently, how big is this in terms of the overall contribution, and how many of the overall 505(b)(2) assets within the liquids portfolio have already been commercialized?
Sharvil Patel
We have around seven launches, I think, and we have 10-plus approvals, and we continue to build a larger pipeline.
Understood, sir. Lastly, also on desidustat, any update in terms of our China partner launching it in the Chinese market and how the ramp-up is happening there?
How big of an opportunity do you think it could be over the next couple of years?
Sharvil Patel
Yes, I think we have achieved the milestones of getting it approved in China now. We have supplied now API for formulation manufacturing in their market.
With the time, this product is naturally reimbursed in their drug list, obviously, we need to get an approval through in the NRDL to gain major part of the share. Having looked at that, there are 120 million CKD patients in China, it's a very, very large market.
The prevalence of anemia is very strong in that market. Looking at all of that and looking at how the peers have done in this space, we see it as a good opportunity.
First, we need to go through the registration and making sure it is available to the reimbursement phase. Once the reimbursement phase goes through, then we can see an uptake in that business.
Maybe in a couple of quarters, we can give more highlight, but we see this being a decent opportunity, a long-term opportunity, but we'll have to wait for another two to three quarters to make sure that all the important approvals go through and the access to the molecule is created in the list.
Understood, sir. Just one last question.
Given that it's an NCE asset, and I presume that, of course, it'll also be under patent protection in the Chinese market. If not as big as Saro in comparison, how much of steady-state sales would this asset generate once it reaches its, let's say, three to four years down the line?
What kind of top-line contribution could be coming from this product on the China market? See,
Sharvil Patel
the opportunity is very difficult to say right now. We have not factored in any meaningful scale in terms of our current year.
As we get experienced in terms of it getting reimbursement through, then we can see it importantly doing well because the other molecule is doing very well, which is already launched. I think they are doing about $200+ million in the Chinese market.
We can see it also being a meaningful contributor to us.
Thank you, sir. Thanks for answering my questions, and all the very best.
Operator
Thank you. The next question is from Kunal Dhamesha.
Kunal Dhamesha
Hello. Can you hear me?
Operator
Yes.
Kunal Dhamesha
Yeah. Dr.
Sharvil, one question on saroglitazar. For the incremental addressable patient pool, one, do we need to do additional studies?
If yes, what would be the size, scope, and duration of that study? With, let's say, initial indication we already applied, would we be going for an expedited process here?
Sharvil Patel
Saro has already been granted priority review by the FDA for its first indication in PBC, so that is on track, and as I said, we are building for pre-launch activities on that. This will be a continuing trial because we have to follow the patients through and do our rolling Phase III, so that will continue.
We're also adding a marginal ALP trial to Saro for certain patients who are marginal ALP issues. That will also expand the opportunity size of the market, which that trial is about to start.
Those are the updates on the key trials.
Kunal Dhamesha
The duration, if you could share, in, let's say, expanded indication, can it be a near-term opportunity, or would take, let's say, two to three years? How should we think about it?
Sharvil Patel
No, it's not. The expanded indication is not a near term.
It'll take two to three years.
Kunal Dhamesha
Sure. Any update on usnoflast for ALS indication?
When is the readout that we expect for that?
Sharvil Patel
No, on usnoflast, as I said, we have couple of trials that we are doing. One is we initiated Phase IIb in the US for ALS, so that is ongoing.
The study is going to enroll 240 patients against the placebo, so that is the way it is moving on. Maybe see it as a FY '28 kind of timeline when we can see some data coming out of that, end of FY '20 late calendar year '28, '28 or early '29.
That's when we'll see the data come out. On the ulcerative colitis trial, we have also looking at that as a potential opportunity also.
We're seeing good Phase IIa data in India, and we hope to move that obviously in India in the next Phase IIb or III, and also potentially evaluate it in the US, which is under evaluation right now.
Kunal Dhamesha
Sure. Thank you.
Operator
Thank you. The next question is from Damayanti Kerai.
Hi. Good afternoon, and thank you for the opportunity.
My first question is for Dr. [unclear] indicated your medium-term goal of [unclear].
For these, what kind of spend you foresee, whether it's towards the SG&A or building up team for specialty, etc.?
Sharvil Patel
We were not able to hear your question, if you don't mind repeating it, please.
Sure. My question was regarding the kind of spend which you foresee for scaling up some of your newer initiative, whether it's MedTech, specialty, biosimilars.
This is also related to how should we see spend required to reach the medium-term goal of getting two-third of revenue from branded products, as you indicated?
Sharvil Patel
We have already invested in biologics and vaccines, so that investment has already gone through. Also, MedTech is a business running and growing business which we acquired and which we also launched in India in the cardiovascular side.
These businesses are already invested in and are baked into our current margin guidances.
As these businesses scale up and no major incremental spend, it's safe to assume we will be seeing margins moving up from the level which you indicated for FY '27?
Sharvil Patel
FY '27, we have guided for a 20
24%, that's right?
Sharvil Patel
24% margin guidance, so that is what we are sticking to.
Okay. On the biosimilars portfolio where you just launched your big product there, there also, what kind of timeline we should assume to see meaningful sales build-up happening?
Sharvil Patel
Biosimilars is already a meaningfully scaled business for us and very profitable, it is not a new business for us.
No, I was specifically asking for the US part. India, obviously, I think you have a very well-established presence, EM as well, but...
Sharvil Patel
US is more like a '29 kind of timeline when we will see that business scale up. We will have a couple of products before, but real meaningful scale-up will come in calendar year '29.
That's helpful. Thank you.
Operator
Thank you. The next question is from Bino.
Hi, good evening, all of you. Can you hear me?
Sharvil Patel
Yes.
Great. Sharvil, I was looking at the US trajectory over next three, four years.
This year we have mirabegron going on plus rosiglitazone should come in. Next year also, partly we have mirabegron and palbociclib should come in.
Beyond that, do you think there could be a dip in US revenues, even if it is a temporary one?
Tushar Shroff
No, we still have a growing pipeline of products beyond this valuable products in the market. In fact, we recently also launched indacaterol/glycopyrronium where we got 180 days exclusivity.
We have a future pipeline of products which are in the 505(b)(2) and ready-to-use formats and other areas, which will all add to meaningful business. We do not see that kind of a fall in the US revenues.
Understood. Thank you.
One bookkeeping question. If I look at the depreciation number consolidated, it has sharply gone up starting 4Q of last year, and 1Q also, again, has gone up.
Part of it could be the acquisitions and related amortization. Is there anything else into it?
Is this the level at which it will continue?
Tushar Shroff
Finance side. I think, largely, it is on account of the acquisitions.
This amount also includes the licensing amortizations that we had because of the mirabegron settlement, so that will be up to the first quarter of FY '27-'28.
Do you mind calling out that number, roughly at least?
Tushar Shroff
We have not called out that number specifically because of the confidentiality.
Okay. Anyway, it will end in the second quarter of FY '28, correct?
Tushar Shroff
Yes, that's correct.
Thank you.
Operator
Thank you. The next question is from Sayan Mukherjee.
Thanks for the follow-up. Just as you mentioned about the brand part of the business becoming two-thirds or more in the medium term, and this year has been more of an investment year for you.
With that business mix changing towards brand from 24% EBITDA margin today, where should you expect, let's say, from a FY '30 perspective, when you achieve those targets, your EBITDA margin to settle at?
Tushar Shroff
I think from the planning point of view, yes, when we are able to scale up our branded business towards the two-thirds, then we should see an improvement in EBITDA margins. Obviously, the first couple of years, now you'll see an investment phase on Saro and some of the other portfolio and also some increase in R&D.
Ideally, we would want to be improving our EBITDA margins to a 28%-30%+ percent range as we move closer to the five-year period.
Thank you.
Operator
Thank you. The next question is from Rashmi Shetty.
Thanks for the opportunity. Am I audible?
Tushar Shroff
Yes. Yeah.
Sir,
just one bookkeeping question. On Assertio, whatever consideration amount, how much are you allocating to goodwill, intangibles, or anything in gross block?
I think
Tushar Shroff
we have a window of 12 months to finalize in terms of what should be the purchase price allocation of this entire consideration. The large part of this will be towards the brand as well as the platform that we have got from the commercial platform that we got from this particular acquisition, large part will be towards the intangibles.
Okay. Amortization and all has not come in in quarter one, right, for this quarter?
Tushar Shroff
Yes, that's correct.
Okay. On your Comfort Click business, how do you see growth for this piece in FY '27 and going ahead?
Tushar Shroff
We are seeing good, strong double-digit growth for the business, and that we see that happen for this year.
Okay. For the entire consumer business also, you see a strong double-digit growth only, right?
Tushar Shroff
We are looking at a double-digit growth.
Okay. How many launches are planned for the US business for this year?
Tushar Shroff
Between 30 to 40, depending on multiple scenarios, but at least 30-plus launches.
Okay. This includes the specialty launches also, right?
Hello?
Tushar Shroff
Yes.
This includes the specialty launches also, right?
Tushar Shroff
Yes.
Okay. Thank you.
That's it from my side.
Operator
Thank you. The next question is from Surya Patra.
Thanks for the opportunity, sir. Sir, in fact, first question is about the gross margin.
Sorry if I am repeating the question because I slightly late joined the call. See, gross margin this quarter had seen a kind of a dip both sequentially as well as YoY despite of the fact that there would be some currency tailwind that would be there.
How should one understand this? Is it entirely due to the kind of a royalty or the commission that we are paying for mirabegron or what is the reason that would be?
Sharvil Patel
Surya, on gross margin perspective, on a quarter-on-quarter, there is, because of this mirabegron settlement, we had the higher cost associated with that because of the arrangement that we had with the innovator. That is impacting on a quarter-on-quarter basis.
Yeah.
Okay. Then is it fair to believe that, sir, then see this mirabegron issue would be there in the first half?
Second half onwards, it would be subsiding substantially. Then second half gross margin scenario will go back to the normalcy situation excluding for the kind of whatever special situation product opportunity that is there with us?
Is that understanding right?
Sharvil Patel
No, I think maybe you can contextually think differently. Mirabegron is a very good profitable business driver, it's not a negative to the business.
In fact, in spite of whatever royalty agreements we have, it still has very strong profitability. I wouldn't say mirabegron is not the negative side of the story, but the positive side of the story because it continues to be semi-exclusive.
Factoring for all of that, we have still guided for a 24% EBITDA margin.
Okay. Kind of a balanced kind of margin trajectory for the all of the quarter that we are indicating that way.
Sure.
Sharvil Patel
That is what we are guiding for.
Sure, sir. Second question is about the saroglitazar US plans.
The launch plans, if you can talk about, and the associated cost along with the likely timeline, what one should think whether it will kind of have a initial cost impact in FY '28, or how should one think if you can just?
Sharvil Patel
As I said, Saro is an FY '28 launch, we can give you better in the last quarter when we are coming near to launch. The first two years will be a build-out phase for the investment that we make, even this year and the coming year, we would see uptake in investment.
That's what we are building for, and that's how we're also guiding in terms of our margins, assuming that there will be investment on Saro.
Okay. Regards the domestic business piece, sir, see, in fact, as you mentioned in the call itself that your performance was one of the best in the semaglutide side because of your own brand as well as the kind of a partnership route what you have adapted.
Whether this is a sustainable kind of a trend even in the subsequent quarter, or it is the initial benefit of channel filling and all that what the street would have seen for everybody? Hence, whether it is a likely sustainable trend, hence, the gross growth in the domestic market should remain elevated and stronger?
How should one think about this semaglutide boosting the kind of a growth momentum here in India?
Sharvil Patel
On Sema, yes, it is a sustainable momentum. Having said so, our 20% growth is not factored around Sema.
Sema is a contributor, but a small contributor to that. Our growth has come from our other products rather than semaglutide.
Okay. Just last one point, sir.
See, we know that this year you have mentioned about a kind of a sustain some single-digit kind of a growth for the US business, but because of the mirabegron impact. Going back again to '28, FY '28, if we talk about, given the pipeline and given the kind of the EBRANCE products exclusivity that is there, again, can we think about double-digit kind of a growth in the US business?
Sharvil Patel
There are all things that we're doing with obviously on the generic as well as on the branded side scaling up. Obviously, we'll see a better profile versus this year.
Sure. Those are the questions, sir.
Thanks for taking all my questions.
Operator
Thank you. The next question is from Vishal Manchanda.
Hi, thanks for the opportunity. Would you be able to share some color on aflibercept biosimilar launch because you were the first one to launch that in India?
Is that shaping up well, and can that be large?
Sharvil Patel
I think the initial traction is good for us. We're seeing it's a very critical product with high-quality specs that is required for this, and we are seeing good results on the launch of the biosimilar.
From the ophthalmology side, this will be a meaningful product for our business.
That's picking up traction well based on your initial assessment?
Sharvil Patel
Yes.
Okay. I also saw you also in-licensed the innovator product also in the same category.
Is that right?
Sharvil Patel
You mean the generic biosimilar of that, right? Yeah.
No, the innovator brand as well is something you have in-licensed. EYLEA, which is the innovator brand, has Zydus in-licensed that as well?
Sharvil Patel
We have not licensed the innovator brand.
Okay. Thank you.
That's all from my side.
Operator
Thank you. We will wait for the queue to assemble.
If anybody wishes to ask the question, please raise your hand from the participant tab on the screen. Thank you very much to Zydus Lifesciences Zydus Lifesciences management team.
Ladies and gentlemen, on behalf of Zydus Lifesciences, that concludes today's conference. Thank you for joining us, and you may now disconnect your line and exit the webinar.
Thank you. Thank you.
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