- Business
- Novartis AG is a Switzerland-based innovative medicines company that researches, develops, manufactures and commercializes prescription therapies for serious diseases. Its principal products include immunology medicines such as Cosentyx for inflammatory diseases, Xolair for allergic conditions and Rhapsido for chronic spontaneous urticaria; cardiovascular, renal and metabolic medicines including Entresto for heart failure, Leqvio for cholesterol reduction, Fabhalta for complement-mediated and renal diseases, and Vanrafia for immunoglobulin A nephropathy; oncology therapies including Kisqali for breast cancer, Pluvicto and Lutathera radioligand therapies, Scemblix for chronic myeloid leukemia, Tafinlar and Mekinist for melanoma and other cancers, Jakavi for myeloproliferative neoplasms, and Ilaris for inflammatory conditions; neuroscience medicines including Kesimpta for multiple sclerosis, Aimovig for migraine, Zolgensma and Itvisma gene therapies for spinal muscular atrophy; and ophthalmology and established medicines. The company operates as a pure-play innovative-medicines business across four core therapeutic areas—cardiovascular-renal-metabolic, immunology, neuroscience and oncology—and prioritizes chemistry, biotherapeutics, gene and cell therapy, radioligand therapy and xRNA platforms. It serves patients, healthcare providers, hospitals, payers and public-health systems globally, with priority commercial geographies comprising the United States, China, Germany and Japan. Novartis was founded in 1996 and is headquartered in Basel, Switzerland. In recent developments, Novartis completed the acquisition of Avidity Biosciences in February 2026, making Avidity an indirect wholly owned subsidiary and adding a muscle-directed antibody oligonucleotide conjugate platform and late-stage neuromuscular programs; completed the acquisitions of Pikavation Therapeutics and Excellergy, including the Exl-111 allergic-disease asset; and entered into an agreement to acquire Myricx Bio to expand its oncology pipeline with B7-H3- and HER2-targeted antibody-drug conjugate candidates and an associated payload platform. The company also recently advanced launches and regulatory activity for Rhapsido, Itvisma and Fabhalta, while submitting a US biologics license application for del-zota, an investigational exon-skipping therapy for Duchenne muscular dystrophy.