- Business
- Pfizer Inc. (NYSE: PFE) is a leading global biopharmaceutical company that discovers, develops, manufactures and markets a broad portfolio of innovative medicines and vaccines. The company offers prescription pharmaceuticals including blockbusters such as Ibrance (palbociclib) for breast cancer; Eliquis (apixaban) for stroke prevention in atrial fibrillation; Prevnar family vaccines for pneumococcal disease; Vyndaqel/Vyndamax (tafamidis) for transthyretin amyloid cardiomyopathy; Xeljanz (tofacitinib) for rheumatoid arthritis and other inflammatory conditions; Paxlovid (nirmatrelvir/ritonavir) for COVID-19 treatment; Comirnaty (COVID-19 vaccine); Lipitor (atorvastatin) for cholesterol management; Norvasc (amlodipine) for hypertension; Lyrica (pregabalin) for neuropathic pain and epilepsy; Viagra (sildenafil) for erectile dysfunction; Zoloft (sertraline) for depression; and Zithromax (azithromycin) for bacterial infections; alongside vaccines like Abrysvo for respiratory syncytial virus; Trumenba for meningococcal disease; and Penbraya for meningococcal groups A, B, C, W, Y; rare disease therapies including Benefix for hemophilia B and Oxbryta for sickle cell disease; oncology products such as Padcev, Xtandi, Ibrance, Besponsa and Lorbrena; inflammation and immunology treatments like Xeljanz, Cibinqo and Eucrisa; internal medicine offerings for cardiovascular, renal, metabolic and obesity indications; and numerous generics, biosimilars and hospital products spanning antivirals, antibiotics, analgesics, anesthetics and infusion therapies. Pfizer operates in more than 180 countries worldwide with a focus on therapeutic areas including oncology, immunology, internal medicine, vaccines, rare diseases, inflammation and neurology serving healthcare professionals, governments, institutions and patients. Founded in 1849 by cousins Charles Pfizer and Charles F. Erhart, the company is headquartered in New York City. In recent developments, Pfizer completed the acquisition of Metsera in November 2025 adding GLP-1 receptor agonists like MET-097i entering Phase 3 and amylin analog MET-233i to bolster its obesity and cardiometabolic pipeline; finalized a global ex-China licensing agreement with 3SBio in July 2025 for undisclosed assets; received U.S. FDA approval in November 2025 for Padcev plus Keytruda combination in certain bladder cancer patients; and continues advancing its diversified R&D platform amid strategic expansions in gene therapy, diagnostics and breakthrough therapies for unmet needs.