- Business
- Peak Bio, Inc. (OTC: PKBOW) is a clinical-stage biopharmaceutical company focused on developing therapeutics addressing significant unmet medical needs in oncology, inflammation, rare and specialty diseases. The company offers a pipeline featuring PHP-303, a Phase 2-ready small molecule neutrophil elastase inhibitor for alpha-1 antitrypsin deficiency disorder (AATD); an antibody-drug-conjugate (ADC) platform incorporating novel toxins such as PH-1 (Thailanstatin), a spliceosome modulator, linkers and cancer-targeting antibodies; and additional programs targeting solid tumors through immune-engaging payloads. Peak Bio, founded in 2015, maintains headquarters in Palo Alto, California, with research operations in the United States and Korea, serving patient populations in autoimmune, inflammatory and oncologic indications. In November 2024, Peak Bio completed a merger with Akari Therapeutics, Plc (Nasdaq: AKTX) in an all-stock transaction as equals, forming a combined entity that continues as Akari Therapeutics with expanded focus on ADCs, geographic atrophy therapies and complementary assets, supported by PIPE financing and an equity line of credit; the merger followed shareholder approval and aims to advance milestones in oncology and inflammatory diseases while addressing Nasdaq compliance.