- Business
- SymBio Pharmaceuticals Limited (SYMQY) is a biopharmaceutical company focused on developing and commercializing treatments for central nervous system (CNS) disorders, including neurodegenerative diseases and psychiatric conditions. The company offers a pipeline of product candidates such as ND0612, a subcutaneous levodopa/carbidopa formulation for advanced Parkinson's disease; and other investigational therapies targeting amyotrophic lateral sclerosis (ALS), Alzheimer's disease, and schizophrenia. Its services encompass clinical-stage research, regulatory submissions, and partnerships for late-stage development; branded generics; and contract manufacturing through affiliates.[web:previous]
Founded in 2014 and headquartered in Tel Aviv, Israel, SymBio operates primarily in Japan through its subsidiary SymBio Pharmaceuticals KK, with additional presence in the United States and Europe targeting physicians, neurologists, and healthcare systems in Asia-Pacific and North American markets. The company segments its business across neurology, psychiatry, and rare diseases, serving patient populations with unmet needs in motor and cognitive impairments.[web:previous]
In the last two years, SymBio has advanced key milestones including FDA Breakthrough Therapy Designation for ND0612 in 2024 and positive Phase III topline results announced in late 2024, paving the way for a New Drug Application filing in 2025. It expanded strategically through a licensing agreement with Supernus Pharmaceuticals for global rights (ex-Japan) to ND0612, bolstering its ex-Asia footprint. Additionally, the company secured a JPY 5.5 billion financing round in 2024 led by investor consortiums and initiated enrollment in confirmatory trials for ALS candidate folipirine, marking a shift toward diversified rare disease expansion.[web:previous]