Renascience Inc.

Renascience Inc.

TTSE:4889
990.00
JPY
-31.00
(-3.04%)
23.12BMarket Cap
Nov 11Next Earn
Renascience Inc.
TSE:4889
(Tokyo Stock Exchange)

Recent

price

990.00

P/E

ratio

- -

div

yld

- -

ROIC.AI

2020
2021
2022
2023
2024
2025
2026
TTM
JPY
5.87
21.37
12.23
7.91
15.27
10.44
5.32
- -
Revenue per Share
-15
-10.19
-22.33
-26.42
-20.32
8.92
-23.39
- -
Basic EPS, GAAP
-14.53
-9.19
-20.34
-22.57
-18.26
-13.94
-22.62
- -
Free Cash Flow per Basic Share
- -
- -
- -
- -
- -
- -
- -
- -
Dividend per Share
50.66
45.77
173.14
146.72
126.4
135.32
241.18
- -
Book Value per Share
49.42
44.69
173.14
146.71
126.4
135.32
241.18
- -
Tangible Book Value per Share
12
10
11
13
13
13
13
13
Basic Weighted Avg Shares
72
210
139
101
194
133
69
- -
Sales/Revenue/Turnover
-254.3
-41.05
-151.32
-332.06
-129.96
-134.77
-520.59
- -
Operating Margin (%)
3
3
3
1
2
- -
- -
- -
Depreciation Expense
-184
-100
-254
-336
-258
113
-301
- -
Net Income, GAAP
- -
- -
- -
- -
- -
21.1
- -
- -
Effective Tax Rate (%)
-255.64
-47.69
-182.51
-333.98
-133.05
85.48
-439.47
- -
Profit Margin (%)
977
1,013
2,390
2,167
1,960
1,720
3,323
- -
Working Capital
380
476
199
310
356
- -
- -
- -
LT Debt
622
562
2,201
1,865
1,607
1,720
3,323
- -
Total Equity
- -
- -
- -
- -
- -
-7.56
- -
- -
Return on Invested Capital (%)
- -
- -
- -
- -
- -
6.16
- -
- -
Return on Capital (%)
- -
-16.91
-18.41
-16.52
-14.88
6.82
-11.95
- -
Return on Common Equity (%)

Capital Structure

JPY

•

in mil. unless spec.
Sep'26
Mar'26
Jun'27
ST Debt
- -
- -
- -
LT Borrowings
- -
- -
- -
LT Finance Leases
- -
- -
- -
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
13
14
14
Market Capitalization
21,559
23,118
21,464

Working Capital

JPY

•

in mil. unless spec.
Sep'26
Mar'26
Jun'27
Total Current Assets
1,683
3,503
- -
Cash, Cash Equivalents & STI
1,566
3,403
- -
Accounts Receivable, Net
- -
- -
- -
Inventories
- -
- -
- -
Total Current Liabilities
115
181
- -
Payables & Accruals
- -
- -
- -
ST Debt
- -
- -
- -
Deferred Revenue
- -
- -
- -

Growth Rates

JPY

•

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
- -
72.61%
93.16%
Free Cash Flow
- -
40.43%
64.45%
Net Income, GAAP
- -
-69.28%
-365.61%
Sales/Revenue/Turnover
- -
-9.66%
-48.34%
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

JPY

•

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2025
- -
- -
- -
- -
133
2026
- -
- -
- -
- -
69
2027
- -
- -
- -
- -
- -

Quarterly Earnings Per Share

JPY

•

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2025
- -
- -
- -
- -
8.92
2026
- -
- -
- -
- -
-23.39
2027
- -
- -
- -
- -
- -

Quarterly Dividends Per Share

JPY

•

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -
2027
- -
- -
- -
- -
- -
Business
Renascience Inc. (4889.T) develops and commercializes pharmaceuticals and medical devices targeting non-communicable aging-related diseases including cancer, diabetes, respiratory diseases and cardiovascular diseases, as well as women's and children's health conditions; its pipeline features RS5614 (TM-5614), a PAI-1 inhibitor in Phase 3 trials for chronic myeloid leukemia, malignant melanoma, non-small cell lung cancer, cutaneous angiosarcoma, interstitial lung disease associated with systemic scleroderma and FGF23-related hypophosphatemic rickets; RS5441, a PAI-1 inhibitor in Phase 1 for dermatological diseases; RS8001 (pyridoxamine), a water-soluble vitamin in Phase 2 for premenstrual syndrome, premenstrual dysphoric mood disorder, autism spectrum disorder and menopausal disorder; RS9001, an approved disposable ultrafine endoscope; and artificial intelligence-based solutions for diabetes treatment, maintenance hemodialysis and diagnostics. Founded in 2000 and headquartered in Sendai City, Miyagi Prefecture, Japan, following its October 2024 relocation from Tokyo, the company operates primarily in Japan through open innovation labs such as TREx at Tohoku University and HiREx at Hiroshima University. Recent developments include regulatory designation of its malignant melanoma drug as a rare disease treatment in September 2024; a joint development agreement with Taipei Medical University (TMU)-Biotech Co., Ltd. in November 2024; an agreement in January 2025 to host Northwestern University's Potocsnak Longevity Institute at TREx; initiation of Phase 3 trials for RS5614 in malignant melanoma in February 2025; and selection as a Top 40 winner in the XPRIZE Healthspan competition in May 2025.