Tsubota Laboratory Incorporated engages in the research, development, and commercialization of pharmaceuticals, medical devices, and health products primarily targeting myopia, dry eye, presbyopia, depression, dementia, sleep improvement, and concentration enhancement; core offerings include innovative eyeglasses such as myopia prevention models utilizing violet light exposure (360-400 nm wavelength), meibomian gland dysfunction treatments like TLM-001, keratoconus therapies, and pipelines for ophthalmic and neurological conditions delivered via a B2B model through joint research, licensing agreements, milestone payments, and royalties. The company operates in the medical equipment manufacturing and biotechnology sectors, serving partner pharmaceutical firms, clinics, and global markets with a focus on Japan, Asia, Europe, China, and the United States. Founded in 2012 and headquartered at CRIK Shinanomachi E7 Building, 9th Floor, Keio University Shinanomachi Campus, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan, Tsubota Laboratory employs approximately 17 people under CEO Kazuo Tsubota. Recent developments include a licensing agreement with an overseas pharmaceutical company on non-clinical and partial clinical trial data for key pipelines, achieving significant profit growth and return to profitability in the third quarter of fiscal 2024; unveiling of the new AEONIA model cosmetics device on November 5, 2025, through partnership with Delavie Sciences for clinic sales channels; and obtaining a manufacturing and marketing license for cosmetics to expand into Japan's cosmetics business while maximizing global pipeline value via strategic partnerships.