Ascendis Pharma A/S
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- Ascendis Pharma A/S, a biopharmaceutical company headquartered in Hellerup, Denmark, and founded in 2007, develops and commercializes TransCon-based therapies addressing unmet needs in endocrinology rare diseases and oncology. The company applies its proprietary TransCon technology platform, which enables sustained release of parent drugs to optimize therapeutic profiles, to create product candidates focused on patient safety, efficacy, tolerability, and convenience. Core approved products include SKYTROFA (lonapegsomatropin-tcgd), a once-weekly treatment for pediatric growth hormone deficiency authorized in the United States and the European Union/EEA and commercially available in the United States; and YORVIPATH (palopegteriparatide), a therapy for adults with hypoparathyroidism authorized in the United States, European Union, EEA, and United Kingdom. The pipeline features investigational candidates such as TransCon CNP (navepegritide), a long-acting prodrug in late-stage development for achondroplasia in children with a U.S. PDUFA target date of February 28, 2026 following FDA priority review and extension; as well as other endocrinology rare disease and oncology programs. Operations span North America, Europe, and rest-of-world markets with research facilities in Germany and offices across Europe and the United States; in 2018, Ascendis formed VISEN Pharmaceuticals, granting it exclusive rights to its endocrinology portfolio including TransCon hGH, TransCon PTH, and TransCon CNP in Greater China, with recent supply framework agreements extending through 2027. Recent developments encompass a September 2024 $150 million capped synthetic royalty financing agreement with Royalty Pharma on U.S. net sales of YORVIPATH to support U.S. launch and global capabilities; a February 2025 authorization of a $25 million share repurchase program; strong third-quarter 2025 financial performance with €143.1 million in YORVIPATH revenue and €50.7 million in SKYTROFA revenue alongside operating profit of €11.0 million; and ongoing pipeline advancements including TransCon CNP regulatory progress.
Company News
Once-Weekly TransCon® CNP (Navepegritide) Receives Positive CHMP Opinion for the Treatment of Achondroplasia in Children
FDA Grants Priority Review to BridgeBio's Dwarfism Drug Filing
Ascendis to Share Latest Advances in Hypoparathyroidism and Achondroplasia Programs at ASBMR 2026
Ascendis Pharma A/S’s (ASND) “Overweight” Rating Reaffirmed at Cantor Fitzgerald
Ascendis Pharma: Back To Full Independence
Ascendis Pharma A/S (ASND) Presents at Morgan Stanley 24th Annual Global Healthcare Conference Transcript
Why Is Ascendis Pharma Stock Trading Lower on Tuesday?
Ascendis to Regain Rights to TransCon® Technology in Metabolic and Cardiovascular Diseases
Ascendis Announces Planned $400 Million Share Repurchase Program
Head-To-Head Analysis: Ascendis Pharma A/S (NASDAQ:ASND) versus MeiraGTx (NASDAQ:MGTX)
First Infant Data from Ascendis Trial of Once-Weekly TransCon CNP (Navepegritide) Presented at ESPE 2026
Ascendis Pharma to Participate in the Morgan Stanley 24th Annual Global Healthcare Conference
Ascendis to Share Its Latest Endocrinology Rare Disease Data at ESPE 2026
Ascendis Pharma, Science Applications International And Other Big Stocks Moving Higher On Monday
Biomarin, Ascendis Reach Mutually Beneficial Agreement Ending Global Patent Disputes
Ascendis and BioMarin Enter Binding Term Sheet for a Global Settlement and License Agreement Related to YUVIWEL® (Navepegritide)
This Ascendis Pharma Analyst Begins Coverage On A Bullish Note; Here Are Top 3 Initiations For Thursday
Ascendis Announces Oral Presentation of Week 104 Data from Its Pivotal Trial of TransCon® CNP (Navepegritide) at ISDS 2026
Eyconis Announces Initiation of First-in-Human Clinical Trial of EYC-0305 in Treatment-Naïve Wet Age-Related Macular Degeneration Patients
Ascendis Pharma A/S (ASND) Q2 2026 Earnings Call Transcript