Percheron Therapeutics Limited, formerly Antisense Therapeutics Limited, is an Australian-listed biopharmaceutical company that develops and commercializes antisense oligonucleotide therapies for rare diseases with significant unmet needs, including Duchenne muscular dystrophy, multiple sclerosis, and acromegaly; its products are in-licensed from Ionis Pharmaceuticals Inc. The company's lead candidate, ATL1102, is an antisense inhibitor of the CD49d receptor investigated as a targeted anti-inflammatory therapy via weekly subcutaneous injection for non-ambulatory Duchenne muscular dystrophy patients, with prior Phase II results showing preservation of upper limb function and promising safety; it has also demonstrated efficacy in reducing brain lesions in relapsing-remitting multiple sclerosis and holds US FDA Orphan Drug Designation for DMD. Additional pipeline assets include ATL1103 (Atesidorsen), an antisense oligonucleotide targeting growth hormone receptor expression to lower insulin-like growth factor-I levels for acromegaly and related disorders, following successful Phase II trials. Founded in 2000 and headquartered in Toorak, Victoria, Australia, the company operates primarily in Australia with global clinical development programs targeting international regulatory approvals, such as the EMA-agreed Paediatric Investigation Plan for ATL1102's planned Phase IIb/III trial in Europe. Recent developments include the appointment of Dr. James Garner as CEO and Managing Director effective August 2023; a capital raise in 2023 to fund the DMD trial through key milestones; and a name change to Percheron Therapeutics Limited approved by shareholders in November 2023 and implemented in December 2023 to reflect its evolved strategy.