Aurinia Pharmaceuticals Inc.
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- Aurinia Pharmaceuticals Inc. (NASDAQ: AUPH) is a fully integrated biopharmaceutical company focused on developing and commercializing therapies for patients with rare autoimmune and kidney-related diseases with high unmet medical needs; it markets LUPKYNIS (voclosporin), the first FDA-approved oral therapy for adult patients with active lupus nephritis, and advances a pipeline including aritinercept (formerly AUR200), a recombinant Fc fusion protein dual inhibitor of B-cell activating factor (BAFF) and a proliferation-inducing ligand (APRIL) targeting autoimmune conditions such as systemic lupus erythematosus and IgA nephropathy, along with other investigational assets like AUR300 for M2 macrophage modulation in fibrotic and inflammatory diseases. The company maintains a collaboration and license agreement with Otsuka Pharmaceutical Co., Ltd. for voclosporin commercialization in certain regions. Aurinia operates globally with a U.S. commercial hub in Rockville, Maryland, research and development activities worldwide, and serves nephrologists, rheumatologists, and patients in autoimmune disease segments. Founded in 1993 and headquartered at 1203-4464 Markham Street in Victoria, British Columbia, Canada, Aurinia recently reported strong LUPKYNIS net product sales growth of 25% year-over-year to approximately $60 million in the first quarter of 2025, supported by updated American College of Rheumatology guidelines and expanded market access; it completed the acquisition of Thunderbolt Pharma, Inc. in July 2025 to secure aritinercept following positive Phase 1 results demonstrating 48-55% immunoglobulin reduction and favorable safety, with Phase 2 trials planned by year-end in multiple autoimmune indications; the company repurchased 12.2 million shares for $98.2 million, approved an additional $150 million share repurchase program, and held $351.8 million in cash equivalents and investments as of its latest quarterly update.
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