C4 Therapeutics, Inc.
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- C4 Therapeutics, Inc. (Nasdaq: CCCC) is a clinical-stage biopharmaceutical company focused on targeted protein degradation to develop novel small-molecule medicines that harness the body's natural protein recycling system to eliminate disease-causing proteins. Founded in 2015 and headquartered in Watertown, Massachusetts, the company leverages its proprietary TORPEDO platform to design degrader therapies, including proteolysis-targeting chimeras (PROTACs), degradable molecular glues, and degrader-antibody conjugates, primarily targeting oncology indications such as multiple myeloma, non-Hodgkin's lymphoma, BRAF V600X-mutated solid tumors including melanoma and colorectal cancer, and non-small cell lung cancer with EGFR L858R mutations. Its pipeline features lead candidates cemsidomide, an oral IKZF1/3 degrader for relapsed/refractory multiple myeloma and non-Hodgkin's lymphoma; CFT1946, a BRAF V600X degrader for solid tumors; and CFT8919, an EGFR L858R degrader licensed to Betta Pharmaceuticals for development in Greater China; alongside earlier-stage programs and discovery efforts in autoimmune diseases through partnerships. Recent developments include pricing a $125 million underwritten offering in October 2025 led by RA Capital Management to fund registrational Phase 2 and Phase 1b trials of cemsidomide, including a clinical trial collaboration with Pfizer for combination with elranatamab in multiple myeloma, with potential additional $225 million from warrants; announcing 2025 milestones such as cemsidomide data presentations, CFT1946 expansion cohorts, and CFT8919 dose escalation results; progress in Biogen collaboration with an IRAK4 degrader advancing to clinic; and discontinuation of certain wholly-owned pipeline elements like the BRAF program to prioritize cemsidomide amid a cash position of $267.3 million as of December 31, 2024, extending runway into 2027.
Company News
Insmed Appoints Two New Directors to Its Board
Reviewing ACADIA Pharmaceuticals (NASDAQ:ACAD) and C4 Therapeutics (NASDAQ:CCCC)
C4 Therapeutics Presents New Biomarker Data from the Cemsidomide Phase 1 Trial with Dexamethasone and Phase 1b Trial with Elranatamab (ELREXFIO®) in Relapsed/Refractory Multiple Myeloma at the 23rd International Myeloma Society (IMS) Annual Meeting
Are Medical Stocks Lagging C4 Therapeutics (CCCC) This Year?
C4 Therapeutics to Present New Biomarker Data on the Immunomodulatory Effects of Cemsidomide in Combination with Dexamethasone from its Phase 1 Relapsed/Refractory Multiple Myeloma Trial at the 23rd International Myeloma Society (IMS) Annual Meeting
Financial Review: C4 Therapeutics (NASDAQ:CCCC) and Alkermes (NASDAQ:ALKS)
Are You Looking for a Top Momentum Pick? Why C4 Therapeutics, Inc. (CCCC) is a Great Choice
C4 Therapeutics, Inc. (CCCC) Reports Q2 Loss, Tops Revenue Estimates
Is C4 Therapeutics (CCCC) Stock Outpacing Its Medical Peers This Year?
C4 Therapeutics, Inc. (CCCC) Is Up 2.65% in One Week: What You Should Know
C4 Therapeutics, Inc. (CCCC) Discusses Evolving Multiple Myeloma Treatments and the Role of IKZF1/3 Degraders Including Cemsidomide Transcript
Are Medical Stocks Lagging C4 Therapeutics (CCCC) This Year?
C4 Therapeutics Presents Phase 1 Data at European Hematology Association (EHA) 2026 Congress Highlighting Cemsidomide as a Potential Best-in-Class IKZF1/3 Degrader for Multiple Myeloma in Heavily Pretreated Relapsed/Refractory Population
C4 Therapeutics "Buy" On Cemsidomide Advancement And Competitor's Positive Readout
C4 Therapeutics (CCCC) Upgraded to Buy: What Does It Mean for the Stock?
C4 Therapeutics to Participate in Upcoming Conferences
C4 Therapeutics Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)
Are Medical Stocks Lagging C4 Therapeutics (CCCC) This Year?
C4 Therapeutics, Inc. (CCCC) Reports Q1 Loss, Lags Revenue Estimates
C4 Therapeutics Reports First Quarter 2026 Financial Results and Recent Business Highlights